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Details

Stereochemistry ACHIRAL
Molecular Formula 2Cr.3O4S
Molecular Weight 392.18
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHROMIC SULFATE

SMILES

[Cr+3].[Cr+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=GRWVQDDAKZFPFI-UHFFFAOYSA-H
InChI=1S/2Cr.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6

HIDE SMILES / InChI

Molecular Formula Cr
Molecular Weight 51.9961
Charge 3
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula O4S
Molecular Weight 96.063
Charge -2
Count
MOL RATIO 3 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Chromium sulfate(III) hexahydrate or chromium sulphate, a trivalent compound of chromium that was investigated as a toxic compound. Experiments on rodent have shown chromium sulfate produced severe and widespread effects in the nasal cavity, larynx, lungs, and mediastinal lymph node. Effects were characterized by the accumulation of foreign material, infiltration of alveolar macrophages, septal cell hyperplasia, and granulomatous and chronic inflammation. Besides, chromium sulphate exerted a disadvantageous effect on the skeleton, as it decreases bone density and resistance.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
CHROMIUM

PubMed

TitleDatePubMed
Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin.
1994 Jun
Thirteen-week subchronic rat inhalation toxicity study with a recovery phase of trivalent chromium compounds, chromic oxide, and basic chromium sulfate.
1999 Dec
Immunosuppressive effect of subchronic exposure to a mixture of eight heavy metals, found as groundwater contaminants in different areas of India, through drinking water in male rats.
2007 Oct
The peripheral quantitative computed tomographic and densitometric analysis of skeletal tissue in male Wistar rats after chromium sulfate treatment.
2017 Sep 21

Patents

Substance Class Chemical
Record UNII
Y0C99N5TMZ
Record Status Validated (UNII)
Record Version
Name Type Language
CHROMIC SULFATE
Common Name English
CHROMIUM SULFATE (2:3)
Systematic Name English
CHROMIUM(III) SULFATE [HSDB]
Common Name English
CHROMIUM(III) SULPHATE
Systematic Name English
CHROMIC SULPHATE
Common Name English
CHROMIC SULFATE [MI]
Common Name English
DICHROMIUM TRISULPHATE
Systematic Name English
CHROMIUM III SULPHATE
Common Name English
CHROMIUM SULPHATE (2:3)
Systematic Name English
NSC-51151
Code English
DICHROMIUM TRISULFATE
Systematic Name English
CHROMIC SULFATE [VANDF]
Common Name English
CHROMIUM(III) SULFATE
Systematic Name English
CHROMIUM III SULFATE
Common Name English
Code System Code Type Description
CAS
10101-53-8 PRIMARY
RXCUI
90402 PRIMARY RxNorm
CHEBI
53471 PRIMARY
ECHA (EC/EINECS)
233-253-2 PRIMARY
SMS_ID
300000044724 PRIMARY
FDA UNII
Y0C99N5TMZ PRIMARY
EPA CompTox
DTXSID20890642 PRIMARY
PUBCHEM
24930 PRIMARY
MERCK INDEX
m3504 PRIMARY Merck Index
DAILYMED
Y0C99N5TMZ PRIMARY
WIKIPEDIA
CHROMIUM(III) SULFATE PRIMARY
HSDB
2543 PRIMARY
NSC
51151 PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY