CHROMIC SULFATE DECAHYDRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2Cr.3O4S.10H2O
Molecular Weight	572.333
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CHROMIC SULFATE DECAHYDRATE

Structure Search

SMILES

O.O.O.O.O.O.O.O.O.O.[Cr+3].[Cr+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=DERXPFSZQYCOIC-UHFFFAOYSA-H

InChI=1S/2Cr.3H2O4S.10H2O/c;;3*1-5(2,3)4;;;;;;;;;;/h;;3*(H2,1,2,3,4);10*1H2/q2*+3;;;;;;;;;;;;;/p-6

HIDE SMILES / InChI

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Cr
Molecular Weight	51.9961
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10630581 | https://www.ncbi.nlm.nih.gov/pubmed/28954488

Chromium sulfate(III) hexahydrate or chromium sulphate, a trivalent compound of chromium that was investigated as a toxic compound. Experiments on rodent have shown chromium sulfate produced severe and widespread effects in the nasal cavity, larynx, lungs, and mediastinal lymph node. Effects were characterized by the accumulation of foreign material, infiltration of alveolar macrophages, septal cell hyperplasia, and granulomatous and chronic inflammation. Besides, chromium sulphate exerted a disadvantageous effect on the skeleton, as it decreases bone density and resistance.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
transmembrane receptor protein tyrosine kinase activity 22 Target ID: GO:0004714 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15924436	Activator 1430

Conditions

Condition	Modality	Targets	Highest Phase	Product
Chromium deficiency 22 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4d01ebb-a36e-44b7-028c-43c0ab2d13b4	Preventing		Approved 8429	CHROMIUM Approved Use Chromium 4 mcg/mL (Chromic Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition. Administration helps to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms. Launch Date 2005

PubMed

Title	Date	PubMed
Silicate antibodies in women with silicone breast implants: development of an assay for detection of humoral immunity.	1996 Mar	8991630
Activation of MAPKs in human bronchial epithelial cells exposed to metals.	1998 Sep	9728050
Thirteen-week subchronic rat inhalation toxicity study with a recovery phase of trivalent chromium compounds, chromic oxide, and basic chromium sulfate.	1999 Dec	10630581
Status of antioxidant defense system in chromium-induced Swiss mice tissues.	2004 Jul	21782722
Immunosuppressive effect of subchronic exposure to a mixture of eight heavy metals, found as groundwater contaminants in different areas of India, through drinking water in male rats.	2007 Oct	17657459
The peripheral quantitative computed tomographic and densitometric analysis of skeletal tissue in male Wistar rats after chromium sulfate treatment.	2017 Sep 21	28954488

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:13:19 GMT 2023` Edited by `admin` on `Fri Dec 15 16:13:19 GMT 2023`
Record UNII	8Q759N78CX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHROMIC SULFATE DECAHYDRATE

Common Name

English

CHROMIC SULPHATE DECAHYDRATE

Common Name

English

CHROMIUM(III) SULFATE HYDRATE

Systematic Name

English

CHROMIUM(III) SULPHATE HYDRATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C579