EFALIZUMAB

Approval Year

Substance Class	Protein
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	XX2MN88N5D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EFALIZUMAB

Official Name

English

ANTI-CD11A

Code

English

EFALIZUMAB [HSDB]

Common Name

English

HU1124

Code

English

HU-1124

Code

English

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Classification Tree

Code System

Code

Selective immunosuppressants

WHO-ATC

L04AA21

Antibody-Receptor Interactions

NDF-RT

N0000175856

Psoriasis

LIVERTOX

NBK548791

SKIN DEISEASES, PAPULOSQUAMOUS

EMA ASSESSMENT REPORTS

RAPTIVA (WITHDRAWN: PSORIASIS)

Biological Agent

NCI_THESAURUS

C20401

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Code System

Code

Type

Description

RXCUI

356988

PRIMARY

RxNorm

CAS

214745-43-4

PRIMARY

INN

8122

PRIMARY

NCI_THESAURUS

C68831

PRIMARY

DRUG CENTRAL

4959

PRIMARY

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Subunit 0

Subunit 1

Subunit 2

Subunit 3

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From	To
1_22	1_96
1_148	1_204
1_224	3_214
1_230	2_230
1_233	2_233

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Related Record

Type

Details


					GDR9WM163L

INTEGRIN ALPHA-L

TARGET -> INHIBITOR


					JA0XKI4FW7

HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I

TARGET -> AGONIST

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Related Record

Type

Details


					XX2MN88N5D

EFALIZUMAB

ACTIVE MOIETY

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C6504H10020N1726O2020S46
MOL_WEIGHT:ESTIMATED	CHEMICAL	ESTIMATED 146173.58 DA (average)

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