PF-3491165

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H29F2N3O5
Molecular Weight	513.5331
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O[C@H](CCN1C(=NC(C(=O)NCC2=CC(F)=CC=C2)=C1C3CC3)C4=CC=C(F)C=C4)C[C@@H](O)CC(O)=O

InChI

InChIKey=MTCOKKTVNVFMCS-FGZHOGPDSA-N

InChI=1S/C27H29F2N3O5/c28-19-8-6-18(7-9-19)26-31-24(27(37)30-15-16-2-1-3-20(29)12-16)25(17-4-5-17)32(26)11-10-21(33)13-22(34)14-23(35)36/h1-3,6-9,12,17,21-22,33-34H,4-5,10-11,13-15H2,(H,30,37)(H,35,36)/t21-,22-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C27H29F2N3O5
Molecular Weight	513.5331
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:57:46 GMT 2023` Edited by `admin` on `Sat Dec 16 18:57:46 GMT 2023`
Record UNII	XPH88BHQ45
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PF-3491165

Code

English

(.BETA.R,.DELTA.R)-5-CYCLOPROPYL-2-(4-FLUOROPHENYL)-4-((((3-FLUOROPHENYL)METHYL)AMINO)CARBONYL)-.BETA.,.DELTA.-DIHYDROXY-1H-IMIDAZOLE-1-HEPTANOIC ACID

Systematic Name

English

(3R,5R)-7-(5-CYCLOPROPYL-2-(4-FLUOROPHENYL)-4-((3-FLUOROPHENYL)METHYLCARBAMOYL)IMIDAZOL-1-YL)-3,5-DIHYDROXY-HEPTANOIC ACID

Systematic Name

English

PF3491165

Code

English

1H-IMIDAZOLE-1-HEPTANOIC ACID, 5-CYCLOPROPYL-2-(4-FLUOROPHENYL)-4-((((3-FLUOROPHENYL)METHYL)AMINO)CARBONYL)-.BETA.,.DELTA.-DIHYDROXY-, (.BETA.R,.DELTA.R)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

24762230

Created by admin on Sat Dec 16 18:57:47 GMT 2023 , Edited by admin on Sat Dec 16 18:57:47 GMT 2023

PRIMARY

CAS

950741-95-4

Created by admin on Sat Dec 16 18:57:47 GMT 2023 , Edited by admin on Sat Dec 16 18:57:47 GMT 2023

PRIMARY

FDA UNII

XPH88BHQ45

Created by admin on Sat Dec 16 18:57:47 GMT 2023 , Edited by admin on Sat Dec 16 18:57:47 GMT 2023

PRIMARY

Related Record Type Details


					NJ8U7PX5HN

PF-3491165 SODIUM

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					XPH88BHQ45

PF-3491165

ACTIVE MOIETY

Comments:

PF-3491165 (Pfizer) was in early development for the treatment of patients with atherosclerosis. No information is available on its mechanism. Phase I trials had been initiated however, Pfizer discontinued the development of this drug. NOTES: Pfizer has discontinued development of PF-3491165 for the treatment of atherosclerosis (Company pipeline, Pfizer, 31 July 2007)