Laventatug

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:07:30 GMT 2025` Edited by `admin` on `Wed Apr 02 19:07:30 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	XKA49HSW7G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Laventatug

Official Name

English

H-gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-69-2*01 (88.5%) -(IGHD) -IGHJ6*05 (81.8%) K120>Q (112), A127>S (119), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (2

Preferred Name

English

Immunoglobulin G1, anti-(human zinc transporter ZIP6) (human-Mus musculus monoclonal BRY812 ?1-chain), disulfide with human-Mus musculus monoclonal BRY812 ?-chain, dimer

Common Name

English

laventatug [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens SLC39A6 (solute carrier family 39 member 6, solute carrier family 39 (metal ion transporter) member 6, solute carrier family 39 (zinc transporter) member 6, LIV-1), ZIP6], humanized monoclonal antibody (laventa

Common Name

English

Code System Code Type Description

FDA UNII

XKA49HSW7G

Created by admin on Wed Apr 02 19:07:30 GMT 2025 , Edited by admin on Wed Apr 02 19:07:30 GMT 2025

PRIMARY

CAS

3009829-91-5

Created by admin on Wed Apr 02 19:07:30 GMT 2025 , Edited by admin on Wed Apr 02 19:07:30 GMT 2025

PRIMARY

INN

13502

Created by admin on Wed Apr 02 19:07:30 GMT 2025 , Edited by admin on Wed Apr 02 19:07:30 GMT 2025

PRIMARY

From	To
4_139	4_199
4_23	4_93
3_139	3_199
3_23	3_93
2_370	2_428
2_264	2_324
2_223	4_219
2_147	2_203
2_22	2_96
1_370	1_428
1_264	1_324
1_232	2_232
1_229	2_229
1_223	3_219
1_147	1_203
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					NUK386L57F

Laventatug Tivedotin

CONJUGATE -> PARENT

Amount:

Related Record Type Details


					XKA49HSW7G

Laventatug

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS	K		LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL