Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2NO3.Ni.6H2O |
| Molecular Weight | 290.7949 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.O.O.O.O.[Ni++].[O-][N+]([O-])=O.[O-][N+]([O-])=O
InChI
InChIKey=AOPCKOPZYFFEDA-UHFFFAOYSA-N
InChI=1S/2NO3.Ni.6H2O/c2*2-1(3)4;;;;;;;/h;;;6*1H2/q2*-1;+2;;;;;;
| Molecular Formula | NO3 |
| Molecular Weight | 62.0049 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Ni |
| Molecular Weight | 58.6934 |
| Charge | 2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: http://onlinelibrary.wiley.com/doi/10.1002/14356007.a17_235.pub2/abstracthttps://www.nicnas.gov.au/chemical-information/imap-assessments/imap-group-assessment-report?assessment_id=883Curator's Comment: description was created based on several sources, including
https://www.cdc.gov/niosh/docs/81-123/pdfs/0445.pdf
Sources: http://onlinelibrary.wiley.com/doi/10.1002/14356007.a17_235.pub2/abstracthttps://www.nicnas.gov.au/chemical-information/imap-assessments/imap-group-assessment-report?assessment_id=883
Curator's Comment: description was created based on several sources, including
https://www.cdc.gov/niosh/docs/81-123/pdfs/0445.pdf
Nickel nitrate, a water soluble salt of Ni is irritating to the eyes, skin and, upon inhalation of the dust, respiratory tract. It may cause skin allergy. Nickel nitrate is a carcinogen, along with most other nickel compounds. The nickel ion is also toxic to aquatic organisms.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Differential Toxicities of Nickel Salts to the Nematode Caenorhabditis elegans. | 2016-08 |
|
| Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cells. | 2011-11 |
|
| Mutagenicity tests with nickel salts in the male mouse. | 1982 |
Sample Use Guides
In Vivo Use Guide
Curator's Comment: The Ni compounds used in this experiment were nickel metal [Ni-M], nickel oxide (green) [NiO(G)], nickel oxide (black) [NiO(B)], nickel subsulfide [Ni3S2], nickel sulfide [NiS], nickel sulfate [NiSO4], nickel chloride [NiCl2], and nickel nitrate [Ni(NO3)2]. The solubilities of the nickel compounds in saline solution were in the following order; [Ni(NO3)2 > NiCl2 > NiSO4] >> [NiS > Ni3S2] > [NiO(B) > Ni-M > NiO(G)]. The Ni level in the visceral organs was higher in the rats given soluble Ni compounds; Ni(NO3)2, NiCl2, NiSO4, than that in the rats receiving other compounds. In the rats to which soluble Ni compounds were administered, 80-90% of the recovered Ni amounts in the examined organs was detected in the kidneys.
Unknown
Route of Administration:
Unknown
| Substance Class |
Chemical
Created
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admin
on
Edited
Mon Mar 31 21:20:32 GMT 2025
by
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Mon Mar 31 21:20:32 GMT 2025
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| Record UNII |
XBT61WLT1J
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| Record Status |
Validated (UNII)
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ANHYDROUS->SOLVATE |
