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Details

Stereochemistry ACHIRAL
Molecular Formula 2NO3.Ni
Molecular Weight 182.7032
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NICKEL NITRATE

SMILES

[Ni++].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI

InChIKey=KBJMLQFLOWQJNF-UHFFFAOYSA-N
InChI=1S/2NO3.Ni/c2*2-1(3)4;/q2*-1;+2

HIDE SMILES / InChI
Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Ni
Molecular Weight 58.6934
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.cdc.gov/niosh/docs/81-123/pdfs/0445.pdf

Nickel nitrate, a water soluble salt of Ni is irritating to the eyes, skin and, upon inhalation of the dust, respiratory tract. It may cause skin allergy. Nickel nitrate is a carcinogen, along with most other nickel compounds. The nickel ion is also toxic to aquatic organisms.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Differential Toxicities of Nickel Salts to the Nematode Caenorhabditis elegans.
2016-08
Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cells.
2011-11
Mutagenicity tests with nickel salts in the male mouse.
1982
Patents

Patents

04533765
2
04639432
2
04988646
2
05980786
5
06054052
2
06306787
2
US5039502
2

Sample Use Guides

In Vivo Use Guide
Curator's Comment: The Ni compounds used in this experiment were nickel metal [Ni-M], nickel oxide (green) [NiO(G)], nickel oxide (black) [NiO(B)], nickel subsulfide [Ni3S2], nickel sulfide [NiS], nickel sulfate [NiSO4], nickel chloride [NiCl2], and nickel nitrate [Ni(NO3)2]. The solubilities of the nickel compounds in saline solution were in the following order; [Ni(NO3)2 > NiCl2 > NiSO4] >> [NiS > Ni3S2] > [NiO(B) > Ni-M > NiO(G)]. The Ni level in the visceral organs was higher in the rats given soluble Ni compounds; Ni(NO3)2, NiCl2, NiSO4, than that in the rats receiving other compounds. In the rats to which soluble Ni compounds were administered, 80-90% of the recovered Ni amounts in the examined organs was detected in the kidneys.
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:00:12 GMT 2025
Edited
by admin
on Mon Mar 31 19:00:12 GMT 2025
Record UNII
50L0S38I2D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NICKEL NITRATE [HSDB]
Preferred Name English
NICKEL NITRATE
HSDB   MI  
Systematic Name English
NICKEL(II) NITRATE
Systematic Name English
NICKEL DINITRATE
Systematic Name English
NICKEL NITRATE [MI]
Common Name English
NITRIC ACID NICKEL (2+) SALT (2:1)
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID70872958
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
ECHA (EC/EINECS)
236-068-5
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
DAILYMED
50L0S38I2D
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
SMS_ID
300000053467
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
MESH
C035197
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
PUBCHEM
25736
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
WIKIPEDIA
NICKEL(II) NITRATE
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
CAS
13138-45-9
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
MERCK INDEX
m7868
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY Merck Index
HSDB
1829
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
FDA UNII
50L0S38I2D
Created by admin on Mon Mar 31 19:00:12 GMT 2025 , Edited by admin on Mon Mar 31 19:00:12 GMT 2025
PRIMARY
Related Record Type Details
Structure of NICKEL NITRATE HEXAHYDRATE
SOLVATE->ANHYDROUS
Structure of NICKEL CATION
PARENT -> SALT/SOLVATE
Structure of NICKEL CATION
PARENT -> SALT/SOLVATE
NIH
NCATS
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