Nicotinonitrile

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H4N2
Molecular Weight	104.1094
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N#CC1=CN=CC=C1

InChI

InChIKey=GZPHSAQLYPIAIN-UHFFFAOYSA-N

InChI=1S/C6H4N2/c7-4-6-2-1-3-8-5-6/h1-3,5H

HIDE SMILES / InChI

Molecular Formula	C6H4N2
Molecular Weight	104.1094
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Dibromidobis(pyridine-3-carbonitrile-κN)zinc(II).	2010-12-18	21522516
Cloning, expression and functional analysis of nicotinate dehydrogenase gene cluster from Comamonas testosteroni JA1 that can hydroxylate 3-cyanopyridine.	2010-07	20119845
6-(4-Amino-phen-yl)-2-eth-oxy-4-(2-thien-yl)nicotinonitrile.	2010-06-26	21588020
Generation of mutant of Rhodococcus rhodochrous PA-34 through chemical mutagenesis for hyperproduction of nitrile hydratase.	2010-06	20587386
Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.	2010-03-15	20153643
Solid and liquid charge-transfer complex formation between 1-methylnaphthalene and 1-alkyl-cyanopyridinium bis{(trifluoromethyl)sulfonyl}imide ionic liquids.	2010-02-28	20145851
6-(4-Bromo-phen-yl)-2-eth-oxy-4-(2,4,5-trimethoxy-phen-yl)nicotinonitrile.	2010-02-17	21580396
6-(4-Bromo-phen-yl)-2-eth-oxy-4-(4-ethoxy-phen-yl)nicotinonitrile.	2009-12-09	21580178
Fluorescence properties of donor acceptor chromophores on newly synthesized pyridine-3-carbonitriles.	2009-11	19626428
New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage.	2009-11	19616348
6-(4-Bromo-phen-yl)-2-eth-oxy-4-(2,4,6-trimethoxy-phen-yl)nicotinonitrile.	2009-10-31	21578493
C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCtheta inhibitors: part II.	2009-10-01	19703774
Pyridine-3-carbonitrile-chloranilic acid-acetonitrile (2/1/2).	2009-09-16	21577921
Purification of a hyperactive nitrile hydratase from resting cells of Rhodococcus rhodochrous PA-34.	2009-09	23100776
New catalytic liquid-phase ammoxidation approach to the preparation of niacin (vitamin B3).	2009-07-07	19462987
Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCtheta inhibitors.	2009-07-01	19447612
Synthesis and therapeutic evaluation of pyridyl based novel mTOR inhibitors.	2009-06-01	19409777
Optimization of crucial reaction conditions for the production of nicotinamide by nitrile hydratase using response surface methodology.	2008-12	18975144
Design and campaign synthesis of pyridine-based histone deacetylase inhibitors.	2008-04-15	18378451
Characterisation of the substrate specificity of the nitrile hydrolyzing system of the acidotolerant black yeast Exophiala oligosperma R1.	2008	19287539
Reactions of sulphate radicals with substituted pyridines: a structure-reactivity correlation analysis.	2007-12-03	17957815
Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability.	2007-10-15	17768051
Novel synthesis of [1]-benzothiepino[5,4-b]pyridine-3-carbonitriles and their anti-inflammatory properties.	2007-03-15	17267228
Bench scale conversion of 3-cyanopyidine to nicotinamide using resting cells of Rhodococcus rhodochrous PA-34.	2007-03	23100637
Isocyanide addition to pyridinium salts. Efficient entry into substituted nicotinonitrile derivatives.	2006-12-07	17134273
Purification and characterization of a nitrilase from Aspergillus niger K10.	2006-12	17061133
Hyperinduction of nitrilases in filamentous fungi.	2006-11	16909267
{Fe(3CNpy)2[Cu(3CNpy)(mu-CN)2]2}: a one-dimensional cyanide-based spin-crossover coordination polymer.	2006-06-12	16749818
Mild hydrolysis of nitriles by Fusarium solani strain O1.	2006	17007419
Novel milrinone analogs of pyridine-3-carbonitrile derivatives as promising cardiotonic agents.	2005-12	16040161
Kinetics and mechanisms of the electron transfer reactions of oxo-centred carboxylate bridged complexes, [Fe3(mu3-O)(O2CR)6L3]ClO4, with verdazyl radicals in acetonitrile solution.	2005-04-21	15824792
Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs.	2005-02	15621268
Supramolecular isomerism in spin crossover networks with aurophilic interactions.	2004-10-21	15489974
Synergy between spin crossover and metallophilicity in triple interpenetrated 3D nets with the NbO structure type.	2003-11-26	14624540
Two-dimensional metamagnet composed of cyano-bridged CuII-WV bimetallic assembly.	2003-11-21	14651098
2-(3-pyridyl)-1,3,8-triazanaphthalene, a product of the catalytic transformation of 3-cyanopyridine.	2003-09	12944659
A rapid and sensitive fluorometric assay method for the determination of nitrilase activity.	2003-06	12549980
New 3-pyridinecarbonitrile derivatives and their antimicrobial properties.	2002-08-29	12197415
Solvent dynamical control of electron-transfer rates in mixed-valence complexes observed by infrared spectral line shape coalescence.	2002-06-05	12033841
Three-dimensional open frameworks based on cobalt(II) and nickel(II) m-pyridinecarboxylates.	2001-08-27	11511208

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:42:00 GMT 2025` Edited by `admin` on `Mon Mar 31 18:42:00 GMT 2025`
Record UNII	X64V0K6260
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Nicotinonitrile

Systematic Name

English

3-Pyridinecarbonitrile

Preferred Name

English

3-PYRIDINECARBONITRILE [HSDB]

Common Name

English

NSC-17558

Code

English

3-Cyanopyridine

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

Nicotinonitrile