Misitatug

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:32:13 GMT 2025` Edited by `admin` on `Wed Apr 02 20:32:13 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	X5F3Q2SE7P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Misitatug

Official Name

English

H-gamma1 heavy chain (1-454) [VH Musmus/Homsap (Mus musculus IGHV4-1*02 (91.8%) -(IGHD) -IGHJ1*01 (100%)/Homo sapiens IGHV3-74*03 (80.6%) -(IGHD) -IGHJ3*01 (85.7%) Q120>A (116), M123>T (119), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens

Preferred Name

English

misitatug [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens MSLN (mesothelin, pre-pro-megakaryocyte-potentiating factor, megakaryocyte-potentiating factor, MPF, CAK1)]

Common Name

English

Immunoglobulin G1, anti-(human mesothelin) (human-Mus musculus monoclonal RC88 ?1-chain), disulfide with human-Mus musculus monoclonal RC88 ?-chain, dimer

Common Name

English

Code System Code Type Description

SMS_ID

300000054743

Created by admin on Wed Apr 02 20:32:13 GMT 2025 , Edited by admin on Wed Apr 02 20:32:13 GMT 2025

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CAS

2767203-01-8

Created by admin on Wed Apr 02 20:32:13 GMT 2025 , Edited by admin on Wed Apr 02 20:32:13 GMT 2025

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INN

12876

Created by admin on Wed Apr 02 20:32:13 GMT 2025 , Edited by admin on Wed Apr 02 20:32:13 GMT 2025

PRIMARY

NCI_THESAURUS

C206943

Created by admin on Wed Apr 02 20:32:13 GMT 2025 , Edited by admin on Wed Apr 02 20:32:13 GMT 2025

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FDA UNII

X5F3Q2SE7P

Created by admin on Wed Apr 02 20:32:13 GMT 2025 , Edited by admin on Wed Apr 02 20:32:13 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_151	2_207
2_227	4_213
2_268	2_328
1_151	1_207
2_374	2_432
3_23	3_87
3_133	3_193
4_23	4_87
4_133	4_193
1_227	3_213
1_233	2_233
1_236	2_236
1_268	1_328
1_374	1_432

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_304
N	2_304

Related Record Type Details


					NS5GTS5FLQ

Misitatug Blivedotin

DERIVATIVE -> PARENT

Amount:


					NS5GTS5FLQ

Misitatug Blivedotin

CONJUGATE->CONJUGATE COMPONENT

Amount:


					J27WDC343N

TARGET->LIGAND

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_454] [2_454]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL