Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H12FNO2S |
| Molecular Weight | 289.325 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C=C1OC)C2=NC3=C(S2)C=CC(F)=C3
InChI
InChIKey=ZRLSVQBGBBYEAZ-UHFFFAOYSA-N
InChI=1S/C15H12FNO2S/c1-18-12-5-3-9(7-13(12)19-2)15-17-11-8-10(16)4-6-14(11)20-15/h3-8H,1-2H3
| Molecular Formula | C15H12FNO2S |
| Molecular Weight | 289.325 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Bioactivation of fluorinated 2-aryl-benzothiazole antitumor molecules by human cytochrome P450s 1A1 and 2W1 and deactivation by cytochrome P450 2S1. | 2012-08-20 |
|
| Synthesis and antitumour evaluation of novel 2-phenylbenzimidazoles. | 2008-10 |
|
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). | 2008-08-28 |
|
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. | 2006-01-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:49:41 GMT 2025
by
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on
Mon Mar 31 21:49:41 GMT 2025
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| Record UNII |
X3XWA9LQ3Q
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| Record Status |
Validated (UNII)
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| Record Version |
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