RANBEZOLID HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H24FN5O6.ClH
Molecular Weight	497.905
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(F)=C(C=C2)N3CCN(CC4=CC=C(O4)[N+]([O-])=O)CC3

InChI

InChIKey=XYGNKPXLGBABKJ-LMOVPXPDSA-N

InChI=1S/C21H24FN5O6.ClH/c1-14(28)23-11-17-13-26(21(29)33-17)15-2-4-19(18(22)10-15)25-8-6-24(7-9-25)12-16-3-5-20(32-16)27(30)31;/h2-5,10,17H,6-9,11-13H2,1H3,(H,23,28);1H/t17-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C21H24FN5O6
Molecular Weight	461.4436
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:03:30 GMT 2023` Edited by `admin` on `Sat Dec 16 11:03:30 GMT 2023`
Record UNII	X26J4H4W8H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RANBEZOLID HYDROCHLORIDE

Common Name

English

N-(((5S)-3-(3-FLUORO-4-(4-((5-NITRO-2-FURYL)METHYL)PIPERAZIN-1-YL)PHENYL)-2-OXO-OXAZOLIDIN-5-YL)METHYL)ACETAMIDE HYDROCHLORIDE

Systematic Name

English

ACETAMIDE, N-(((5S)-3-(3-FLUORO-4-(4-((5-NITRO-2-FURANYL)METHYL)-1-PIPERAZINYL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

RBX-7644

Code

English

RBX7644

Code

English

N-(((5S)-3-(3-FLUORO-4-(4-((5-NITRO-2-FURYL)METHYL)PIPERAZIN-1-YL)PHENYL)-2-OXO-1,3-OXAZOLIDIN-5-YL)METHYL)ACETAMIDE HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

CAS

392659-39-1

Created by admin on Sat Dec 16 11:03:30 GMT 2023 , Edited by admin on Sat Dec 16 11:03:30 GMT 2023

PRIMARY

PUBCHEM

6918631

Created by admin on Sat Dec 16 11:03:30 GMT 2023 , Edited by admin on Sat Dec 16 11:03:30 GMT 2023

PRIMARY

FDA UNII

X26J4H4W8H

Created by admin on Sat Dec 16 11:03:30 GMT 2023 , Edited by admin on Sat Dec 16 11:03:30 GMT 2023

PRIMARY

Related Record Type Details


					G3NB6JBL8A

RANBEZOLID

ACTIVE MOIETY

Comments:

The chemical synthesis of Ranbezolid hydrochloride. The antibacterial activity of RBx-7644 is due to the 5(S)-acetamidomethyl configuration at the oxazolidinone ring, and thus, asymmetric synthesis of only the 5(S)-enantiomer was desirable.