Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C21H24FN5O6 |
Molecular Weight | 461.4436 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(F)=C(C=C2)N3CCN(CC4=CC=C(O4)[N+]([O-])=O)CC3
InChI
InChIKey=PWHNTOQANLCTHN-KRWDZBQOSA-N
InChI=1S/C21H24FN5O6/c1-14(28)23-11-17-13-26(21(29)33-17)15-2-4-19(18(22)10-15)25-8-6-24(7-9-25)12-16-3-5-20(32-16)27(30)31/h2-5,10,17H,6-9,11-13H2,1H3,(H,23,28)/t17-/m0/s1
Molecular Formula | C21H24FN5O6 |
Molecular Weight | 461.4436 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:03:29 GMT 2023
by
admin
on
Sat Dec 16 11:03:29 GMT 2023
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Record UNII |
G3NB6JBL8A
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Record Status |
Validated (UNII)
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Record Version |
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-
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496993
Created by
admin on Sat Dec 16 11:03:29 GMT 2023 , Edited by admin on Sat Dec 16 11:03:29 GMT 2023
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DTXSID701029733
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admin on Sat Dec 16 11:03:29 GMT 2023 , Edited by admin on Sat Dec 16 11:03:29 GMT 2023
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392659-38-0
Created by
admin on Sat Dec 16 11:03:29 GMT 2023 , Edited by admin on Sat Dec 16 11:03:29 GMT 2023
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G3NB6JBL8A
Created by
admin on Sat Dec 16 11:03:29 GMT 2023 , Edited by admin on Sat Dec 16 11:03:29 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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ACTIVE MOIETY |
Summary of MICs (micrograms per milliliter) of Ranbezolid for S. aureus strains.
Methicillin-resistant S. aureus(n 68): MIC range = 0.25-4, MIC50 = 2, MIC90 = 4
Methicillin-susceptible S. aureus(n 65): MIC range = 0.5-4, MIC50 = 2, MIC90 = 2
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ACTIVE MOIETY |
For 260 pneumococcal and 266 staphylococcal strains, ranbezolid MICs ranged from 0.06 to 4 .MU.g/ml. The MICs for pneumococci were similar irrespective of the strains' .BETA.-lactam, macrolide, or quinolone susceptibilities, and ranbezolid MICs for coagulase-negative staphylococci were lower than those for Staphylococcus aureus. Ranbezolid was bacteriostatic against pneumococci. Ranbezolid MICs were similar to or lower than those of linezolid.
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