LIMIGLIDOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H22N4
Molecular Weight	258.362
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCN1C2=CC=CC=C2N3CCN=C13

InChI

InChIKey=AQUZIHYIKZOILJ-UHFFFAOYSA-N

InChI=1S/C15H22N4/c1-3-17(4-2)11-12-19-14-8-6-5-7-13(14)18-10-9-16-15(18)19/h5-8H,3-4,9-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H22N4
Molecular Weight	258.362
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/26033587 | https://www.medkoo.com/products/8100

Limiglidole belongs to the class of benzimidazole derivatives exhibiting various biological activities including inhibition of platelet aggregation and prolongation of clotting time in animal models. It inhibited platelet aggregation induced by ADP. Antithrombotic activity of hypoglycemic compound limiglidole that exhibits antiplatelet activity 2-fold exceeded activity of antiplatelet agent acetylsalicylic acid in the mouse model of systemic collagen-epinephrine thrombosis. Antithrombogenic properties of limiglidole are beneficial in the treatment of diabetes mellitus.

Approval Year

PubMed

Title	Date	PubMed
Antithrombotic Activity of a New Hypoglycemic Compound Limiglidole in Mouse Model of Cell Thrombosis.	2015 May	26033587

Sample Use Guides

In Vivo Use Guide

Single dose 36 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:01:46 GMT 2023` Edited by `admin` on `Fri Dec 15 16:01:46 GMT 2023`
Record UNII	X0U1YVN4X9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LIMIGLIDOLE

Official Name

English

limiglidole [INN]

Common Name

English

2-(2,3-DIHYDRO-9H-IMIDAZO(1,2-A)BENZIMIDAZOL-9-YL)-N,N-DIMETHYLETHANAMINE

Systematic Name

English

Code System Code Type Description

FDA UNII

X0U1YVN4X9