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Details

Stereochemistry MIXED
Molecular Formula C20H24N2O5.ClH
Molecular Weight 408.876
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEDROXALOL HYDROCHLORIDE

SMILES

Cl.CC(CCC1=CC2=C(OCO2)C=C1)NCC(O)C3=CC(C(N)=O)=C(O)C=C3

InChI

InChIKey=YYWISFWLJSVFOF-UHFFFAOYSA-N
InChI=1S/C20H24N2O5.ClH/c1-12(2-3-13-4-7-18-19(8-13)27-11-26-18)22-10-17(24)14-5-6-16(23)15(9-14)20(21)25;/h4-9,12,17,22-24H,2-3,10-11H2,1H3,(H2,21,25);1H

HIDE SMILES / InChI

Molecular Formula C20H24N2O5
Molecular Weight 372.415
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Medroxalol is a competitive antagonist at alpha1-adrenergic receptors and beta1-adrenergic receptors. Medroxalol also an agonist at beta2-adrenergic receptors. Medroxalol exerts antihypertensive and vasodilating effects. It was concluded that the principal action of medroxalol was to produce a fall in blood pressure by decreasing peripheral vascular resistance more than cardiac output.

Approval Year

PubMed

Substance Class Chemical
Record UNII
X0041CUE0M
Record Status Validated (UNII)
Record Version