U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H6N2
Molecular Weight 94.1145
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-Aminopyridine

SMILES

NC1=NC=CC=C1

InChI

InChIKey=ICSNLGPSRYBMBD-UHFFFAOYSA-N
InChI=1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)

HIDE SMILES / InChI

Molecular Formula C5H6N2
Molecular Weight 94.1145
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
N-glycan structures of human transferrin produced by Lymantria dispar (gypsy moth) cells using the LdMNPV expression system.
2003-07
Investigations into the interactions between DNA and conformationally constrained pyridylamineplatinum(II) analogues of AMD473.
2003-06-02
Speciation study of the anti-inflammatory drug tenoxicam (Htenox) with Cu(II): X-ray crystal structure of [Cu(tenox)(2)(py)(2)].EtOH.
2003-06-01
Localization of defined carbohydrate epitopes in bovine polysialylated NCAM.
2003-05-27
Regioselective substitution of 6,7-dichloroquinoline-5,8-dione: synthesis and X-ray crystal structure of 4a,10,11-triazabenzo[3,2-a]fluorene-5,6-diones.
2003-04-17
Distance dependence of electron transfer across peptides with different secondary structures: the role of Peptide energetics and electronic coupling.
2003-04-02
Thermodynamic, kinetic and structural studies on the mixed ligand complexes of palladium(II) with tridentate and monodentate ligands.
2003-03-01
Bis(2-aminopyridinium) maleate.
2003-03
Plant cultured cells expressing human beta1,4-galactosyltransferase secrete glycoproteins with galactose-extended N-linked glycans.
2003-03
Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors.
2003-02-24
Structural modulation of Cu(I) and Cu(II) complexes of sterically hindered tripyridine ligands by the bridgehead alkyl groups.
2003-02-24
Magnetic interaction of pyridyl-substituted thioaminyl stable free radicals.
2003-02-21
Reduced inotropic heart response in selenium-deficient mice relates with inducible nitric oxide synthase.
2003-02
NMR evaluation of the configurational stability of Cu(I) complexes.
2003-01-27
An HIV reverse transcriptase-selective nucleoside chain terminator.
2003-01-22
Syntheses and structures of isoindoline complexes of Zn(II) and Cu(II): an unexpected trinuclear Zn(II) complex.
2003-01-13
Structural chemistry and In vitro antitubercular activity of acetylpyridine benzoyl hydrazone and its copper complex against Mycobacterium smegmatis.
2003-01-06
Could redox-switched binding of a redox-active ligand to a copper(II) centre drive a conformational proton pump gate? A synthetic model study.
2003-01-03
Selective complex formation of some chromogenic calix[4]arene derivatives detected by Fourier transform infrared spectroscopy 1. Solution experiments.
2003-01-01
2-aminopyridinium benzoate.
2003-01
Syntheses and magnetic properties of hexanuclear [Cp2Mn3(L1)4]2 and octanuclear [Mn8(L2)12(mu 4-O)2] (L1 = 2-HNC5H5N, L2 = 2-NH-3-Br-5-MeC5H3N, Cp = C5H5).
2002-12-21
[N.1.1]-(2,6)-Pyridinophanes: a new ligand type imposing unusual metal coordination geometries.
2002-12-16
Hydrogen bond vibrations of 2-aminopyridine.2-pyridone, a Watson-Crick analogue of adenine.uracil.
2002-12-04
Analysis of fluorogenic Smith degradation products of 7-(1,3-disulfonaphtyl)amino-disaccharides for linkage position analysis of carbohydrates.
2002-12
Antitumor agents. 2. Synthesis, structure-activity relationships, and biological evaluation of substituted 5H-pyridophenoxazin-5-ones with potent antiproliferative activity.
2002-11-21
Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity.
2002-11-21
Amination of pyridylketenes: experimental and computational studies of strong amide enol stabilization by the 2-pyridyl group.
2002-11-20
Example of highly stereoregulated ruthenium amidine complex formation: synthesis, crystal structures, and spectral and redox properties of the complexes [Ru(II)(trpy)[NC(5)H(4)-CH=N-N(C(6)H(5))C(CH(3))=NH]](ClO(4))(2) (1) and [Ru(II)(trpy)(NC(5)H(4)-CH=N-NH-C(6)H(5))Cl]ClO(4) (2) (trpy = 2,2':6',2"-terpyridine).
2002-11-04
Synthesis and characterization of new linear pi-conjugated molecules containing bis(ethynylpyridine) units with a benzothiadiazole spacer.
2002-11-01
Synthesis of some novel quinoline-3-carboxylic acids and pyrimidoquinoline derivatives as potential antimicrobial agents.
2002-11
2-Aminopyridinium-succinate-succinic acid (2/1/1).
2002-11
Solid-phase synthesis of imidazo[1,2-a]pyridine using sodium benzenesulfinate as a traceless linker.
2002-10-31
The unusual role of CO transfer in molybdenum-catalyzed asymmetric alkylations.
2002-10-30
Ru3(CO)12-catalyzed C-H/CO/olefin coupling of N-pyridylindolines. Direct carbonylation at a C-H bond delta to the pyridine nitrogen.
2002-10-18
Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding.
2002-10-10
X-ray diffraction and (1)H NMR in solution: structural determination of lanthanide complexes of a Py(2)N(6)Ac(4) ligand.
2002-10-07
Potent and selective inhibitors of PDGF receptor phosphorylation. 2. Synthesis, structure activity relationship, improvement of aqueous solubility, and biological effects of 4-[4-(N-substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives.
2002-09-26
Enzymatic synthesis and characterization of oligosaccharides structurally related to the repeating unit of Pullulan.
2002-09-20
A mild method for the formation and in situ reaction of imidoyl chlorides: conversion of pyridine-1-oxides to 2-aminopyridine amides.
2002-09-05
Site of protonation of nicotine and nornicotine in the gas phase: pyridine or pyrrolidine nitrogen?
2002-09-04
N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases.
2002-09
Alkylation reactions of [WS(4)](2)(-) and [(eta(5)-C(5)Me(5))WS(3)](-) with 2,6-bis(bromomethyl)pyridine: the first isolation of bisalkylated tetrathiometalate WS(2)[2,6-(SCH(2))(2)(C(5)H(3)N)].
2002-08-12
Studies on synthesis and infrared and fluorescence spectra of new europium and terbium complexes with an amide-based open-chain crown ether.
2002-08
Co(II)-regulated substrate specificity of cytosolic alpha-mannosidase.
2002-08
Nucleophilic attack at pyridine nitrogen and its use to access a novel mono-anionic ligand for iron-based ethylene polymerisation catalysts.
2002-07-21
Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
2002-07-18
Examination of molar-based distribution of A, B and C chains of amylopectin by fluorescent labeling with 2-aminopyridine.
2002-07-16
Exploring routes to stabilize a cationic pyridoxamine in an artificial transaminase: site-directed mutagenesis versus synthetic cofactors.
2002-07
New stereoselective reaction of methylglyoxal with 2-aminopyridine and adenine derivatives: formation of imino acid-nucleic base derivatives in water under mild conditions.
2002-05-21
Properties of some alkyl substituted phthalocyanines and related macrocycles.
2002
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:45:09 GMT 2025
Edited
by admin
on Mon Mar 31 18:45:09 GMT 2025
Record UNII
WSX981HEWU
Record Status Validated (UNII)
Record Version
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Name Type Language
.ALPHA.-AMINOPYRIDINE
MI  
Preferred Name English
2-Aminopyridine
HSDB  
Systematic Name English
MEPYRAMINE MALEATE IMPURITY C [EP IMPURITY]
Common Name English
NSC-431
Code English
TENOXICAM IMPURITY A [EP IMPURITY]
Common Name English
.ALPHA.-AMINOPYRIDINE [MI]
Common Name English
2-PYRIDINAMINE
Systematic Name English
PYRIDIN-2-AMINE
Systematic Name English
PIROXICAM RELATED COMPOUND A [USP-RS]
Common Name English
2-AMINOPYRIDINE [HSDB]
Common Name English
AMINOPYRIDINE, 2-
Systematic Name English
PIROXICAM IMPURITY A [EP IMPURITY]
Common Name English
Code System Code Type Description
SMS_ID
100000142926
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
HSDB
2068
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
MERCK INDEX
m1739
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID0024505
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
CAS
504-29-0
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
PUBCHEM
10439
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
MESH
C032439
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
NSC
431
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
WIKIPEDIA
2-AMINOPYRIDINE
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
ECHA (EC/EINECS)
207-988-4
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
RS_ITEM_NUM
1544519
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
FDA UNII
WSX981HEWU
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
EVMPD
SUB117598
Created by admin on Mon Mar 31 18:45:09 GMT 2025 , Edited by admin on Mon Mar 31 18:45:09 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
PARENT -> IMPURITY
correction factors: for the calculation of content, multiply the peak areas of the following impurities by the corresponding correction factor: impurity A = 0.2
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
ACTIVE MOIETY