U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H6N2
Molecular Weight 94.1145
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-AMINOPYRIDINE

SMILES

NC1=NC=CC=C1

InChI

InChIKey=ICSNLGPSRYBMBD-UHFFFAOYSA-N
InChI=1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)

HIDE SMILES / InChI

Molecular Formula C5H6N2
Molecular Weight 94.1145
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Co(II)-regulated substrate specificity of cytosolic alpha-mannosidase.
2002 Aug
Alkylation reactions of [WS(4)](2)(-) and [(eta(5)-C(5)Me(5))WS(3)](-) with 2,6-bis(bromomethyl)pyridine: the first isolation of bisalkylated tetrathiometalate WS(2)[2,6-(SCH(2))(2)(C(5)H(3)N)].
2002 Aug 12
Analysis of fluorogenic Smith degradation products of 7-(1,3-disulfonaphtyl)amino-disaccharides for linkage position analysis of carbohydrates.
2002 Dec
Syntheses and magnetic properties of hexanuclear [Cp2Mn3(L1)4]2 and octanuclear [Mn8(L2)12(mu 4-O)2] (L1 = 2-HNC5H5N, L2 = 2-NH-3-Br-5-MeC5H3N, Cp = C5H5).
2002 Dec 21
Hydrogen bond vibrations of 2-aminopyridine.2-pyridone, a Watson-Crick analogue of adenine.uracil.
2002 Dec 4
Exploring routes to stabilize a cationic pyridoxamine in an artificial transaminase: site-directed mutagenesis versus synthetic cofactors.
2002 Jul
A convenient synthesis of 2-(alkylamino)pyridines.
2002 Jul 12
Examination of molar-based distribution of A, B and C chains of amylopectin by fluorescent labeling with 2-aminopyridine.
2002 Jul 16
Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
2002 Jul 18
Nucleophilic attack at pyridine nitrogen and its use to access a novel mono-anionic ligand for iron-based ethylene polymerisation catalysts.
2002 Jul 21
Potentiometric and spectrofluorimetric studies on complexation of tenoxicam with some metal ions.
2002 Jun 1
Novel vanadium(V) compounds with a layer structure: synthesis, crystal structures, and solid state NMR spectroscopy of [(VO(2))(2)(4,4'-bpy)(0.5)(4,4'-Hbpy)(XO(4))] x H(2)O (X = P and As).
2002 Jun 3
New stereoselective reaction of methylglyoxal with 2-aminopyridine and adenine derivatives: formation of imino acid-nucleic base derivatives in water under mild conditions.
2002 May 21
Synthesis of some novel quinoline-3-carboxylic acids and pyrimidoquinoline derivatives as potential antimicrobial agents.
2002 Nov
2-Aminopyridinium-succinate-succinic acid (2/1/1).
2002 Nov
Synthesis and characterization of new linear pi-conjugated molecules containing bis(ethynylpyridine) units with a benzothiadiazole spacer.
2002 Nov 1
Amination of pyridylketenes: experimental and computational studies of strong amide enol stabilization by the 2-pyridyl group.
2002 Nov 20
Antitumor agents. 2. Synthesis, structure-activity relationships, and biological evaluation of substituted 5H-pyridophenoxazin-5-ones with potent antiproliferative activity.
2002 Nov 21
Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity.
2002 Nov 21
Example of highly stereoregulated ruthenium amidine complex formation: synthesis, crystal structures, and spectral and redox properties of the complexes [Ru(II)(trpy)[NC(5)H(4)-CH=N-N(C(6)H(5))C(CH(3))=NH]](ClO(4))(2) (1) and [Ru(II)(trpy)(NC(5)H(4)-CH=N-NH-C(6)H(5))Cl]ClO(4) (2) (trpy = 2,2':6',2"-terpyridine).
2002 Nov 4
Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding.
2002 Oct 10
Ru3(CO)12-catalyzed C-H/CO/olefin coupling of N-pyridylindolines. Direct carbonylation at a C-H bond delta to the pyridine nitrogen.
2002 Oct 18
The unusual role of CO transfer in molybdenum-catalyzed asymmetric alkylations.
2002 Oct 30
Solid-phase synthesis of imidazo[1,2-a]pyridine using sodium benzenesulfinate as a traceless linker.
2002 Oct 31
X-ray diffraction and (1)H NMR in solution: structural determination of lanthanide complexes of a Py(2)N(6)Ac(4) ligand.
2002 Oct 7
N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases.
2002 Sep
Enzymatic synthesis and characterization of oligosaccharides structurally related to the repeating unit of Pullulan.
2002 Sep 20
Potent and selective inhibitors of PDGF receptor phosphorylation. 2. Synthesis, structure activity relationship, improvement of aqueous solubility, and biological effects of 4-[4-(N-substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives.
2002 Sep 26
Site of protonation of nicotine and nornicotine in the gas phase: pyridine or pyrrolidine nitrogen?
2002 Sep 4
A mild method for the formation and in situ reaction of imidoyl chlorides: conversion of pyridine-1-oxides to 2-aminopyridine amides.
2002 Sep 5
Regioselective substitution of 6,7-dichloroquinoline-5,8-dione: synthesis and X-ray crystal structure of 4a,10,11-triazabenzo[3,2-a]fluorene-5,6-diones.
2003 Apr 17
Distance dependence of electron transfer across peptides with different secondary structures: the role of Peptide energetics and electronic coupling.
2003 Apr 2
Reduced inotropic heart response in selenium-deficient mice relates with inducible nitric oxide synthase.
2003 Feb
Magnetic interaction of pyridyl-substituted thioaminyl stable free radicals.
2003 Feb 21
Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors.
2003 Feb 24
Structural modulation of Cu(I) and Cu(II) complexes of sterically hindered tripyridine ligands by the bridgehead alkyl groups.
2003 Feb 24
2-aminopyridinium benzoate.
2003 Jan
Selective complex formation of some chromogenic calix[4]arene derivatives detected by Fourier transform infrared spectroscopy 1. Solution experiments.
2003 Jan 1
Syntheses and structures of isoindoline complexes of Zn(II) and Cu(II): an unexpected trinuclear Zn(II) complex.
2003 Jan 13
An HIV reverse transcriptase-selective nucleoside chain terminator.
2003 Jan 22
NMR evaluation of the configurational stability of Cu(I) complexes.
2003 Jan 27
Could redox-switched binding of a redox-active ligand to a copper(II) centre drive a conformational proton pump gate? A synthetic model study.
2003 Jan 3
Structural chemistry and In vitro antitubercular activity of acetylpyridine benzoyl hydrazone and its copper complex against Mycobacterium smegmatis.
2003 Jan 6
Localization of defined carbohydrate epitopes in bovine polysialylated NCAM.
2003 Jan-Feb
N-glycan structures of human transferrin produced by Lymantria dispar (gypsy moth) cells using the LdMNPV expression system.
2003 Jul
Speciation study of the anti-inflammatory drug tenoxicam (Htenox) with Cu(II): X-ray crystal structure of [Cu(tenox)(2)(py)(2)].EtOH.
2003 Jun 1
Investigations into the interactions between DNA and conformationally constrained pyridylamineplatinum(II) analogues of AMD473.
2003 Jun 2
Bis(2-aminopyridinium) maleate.
2003 Mar
Plant cultured cells expressing human beta1,4-galactosyltransferase secrete glycoproteins with galactose-extended N-linked glycans.
2003 Mar
Thermodynamic, kinetic and structural studies on the mixed ligand complexes of palladium(II) with tridentate and monodentate ligands.
2003 Mar 1
Patents
Substance Class Chemical
Created
by admin
on Thu Jul 06 00:41:25 UTC 2023
Edited
by admin
on Thu Jul 06 00:41:25 UTC 2023
Record UNII
WSX981HEWU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2-AMINOPYRIDINE
HSDB  
Systematic Name English
MEPYRAMINE MALEATE IMPURITY C [EP IMPURITY]
Common Name English
NSC-431
Code English
.ALPHA.-AMINOPYRIDINE
MI  
Common Name English
TENOXICAM IMPURITY A [EP IMPURITY]
Common Name English
.ALPHA.-AMINOPYRIDINE [MI]
Common Name English
2-PYRIDINAMINE
Systematic Name English
PYRIDIN-2-AMINE
Systematic Name English
PIROXICAM RELATED COMPOUND A [USP-RS]
Common Name English
2-AMINOPYRIDINE [HSDB]
Common Name English
AMINOPYRIDINE, 2-
Systematic Name English
PIROXICAM IMPURITY A [EP IMPURITY]
Common Name English
Code System Code Type Description
SMS_ID
100000142926
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
HSDB
2068
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
MERCK INDEX
M1739
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID0024505
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
CAS
504-29-0
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
PUBCHEM
10439
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
MESH
C032439
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
NSC
431
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
WIKIPEDIA
2-AMINOPYRIDINE
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
ECHA (EC/EINECS)
207-988-4
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
RS_ITEM_NUM
1544519
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
FDA UNII
WSX981HEWU
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
EVMPD
SUB117598
Created by admin on Thu Jul 06 00:41:25 UTC 2023 , Edited by admin on Thu Jul 06 00:41:25 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
correction factors: for the calculation of content, multiply the peak areas of the following impurities by the corresponding correction factor: impurity A = 0.2
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
For the calculation of contents, multiply the peak areas by 0.6
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
ACTIVE MOIETY