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Details

Stereochemistry ACHIRAL
Molecular Formula F6S
Molecular Weight 146.055
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Sulfur hexafluoride

SMILES

FS(F)(F)(F)(F)F

InChI

InChIKey=SFZCNBIFKDRMGX-UHFFFAOYSA-N
InChI=1S/F6S/c1-7(2,3,4,5)6

HIDE SMILES / InChI

Molecular Formula F6S
Molecular Weight 146.055
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

SULFUR HEXAFLUORIDE is a component of LUMASON® (sulfur hexafluoride lipid-type A microspheres). It is an ultrasound contrast agent indicated for use in the heart echocardiography and in ultrasonography of the liver and the urinary tract. The sulfur hexafluoride lipid microspheres are composed of SF6 gas in the core surrounded by an outer shell monolayer of phospholipids with palmitic acid as a stabilizer.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
LUMASON
Diagnostic
LUMASON
Diagnostic
LUMASON

T1/2

ValueDoseCo-administeredAnalytePopulation
10 min
0.3 mL/kg single, intravenous
SULFUR HEXAFLUORIDE blood
Homo sapiens

Doses

AEs

Overview

CYP3A4CYP2C9CYP2D6hERG

OverviewOther

Other InhibitorOther SubstrateOther Inducer

Drug as victim

Tox targets

Sample Use Guides

In Vivo Use Guide
Echocardiography: After reconstitution, administer LUMASON® 2 mL as an intravenous injection in adult patients. Ultrasonography of the liver in adults: After reconstitution, administer LUMASON® 2.4 mL as an intravenous injection.
Route of Administration: Intravenous
Substance Class Chemical
Record UNII
WS7LR3I1D6
Record Status Validated (UNII)
Record Version