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Details

Stereochemistry ACHIRAL
Molecular Formula C20H23N3O2
Molecular Weight 337.4155
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXIPEROMIDE

SMILES

O=C1NC2=C(C=CC=C2)N1C3CCN(CCOC4=CC=CC=C4)CC3

InChI

InChIKey=NVDBBGBUTKLRSN-UHFFFAOYSA-N
InChI=1S/C20H23N3O2/c24-20-21-18-8-4-5-9-19(18)23(20)16-10-12-22(13-11-16)14-15-25-17-6-2-1-3-7-17/h1-9,16H,10-15H2,(H,21,24)

HIDE SMILES / InChI

Molecular Formula C20H23N3O2
Molecular Weight 337.4155
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Oxiperomide was developed as a dopamine-receptor antagonist. Clinical trials have shown that this drug decreased dyskinesia in patients with Parkinson's disease receiving levodopa or other dopamine agonists without necessarily increasing Parkinsonian symptoms. However, information about the further development of this drug is not available.

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
Oxiperomide was given in 5 mg tablet doses twice daily, starting at 10 mg/day and increasing weekly by 5-10 mg/day intervals, up to 40 mg/day, until an optimal dose was achieved or side effects developed.
Route of Administration: Oral
Substance Class Chemical
Record UNII
WRO75M6RW2
Record Status Validated (UNII)
Record Version