VUF-5681

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H19N3
Molecular Weight	193.2887
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VUF-5681

Structure Search

SMILES

C(CC1CCNCC1)CC2=CN=CN2

InChI

InChIKey=YPGRNKJNOSUCLY-UHFFFAOYSA-N

InChI=1S/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14)

HIDE SMILES / InChI

Molecular Formula	C11H19N3
Molecular Weight	193.2887
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Histamine H3 receptor 44 Target ID: CHEMBL264 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15115383	Antagonist 2778		8.35 null [pKi]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:11:56 UTC 2023` Edited by `admin` on `Sat Dec 16 18:11:56 UTC 2023`
Record UNII	WR5V5TB2TR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VUF-5681

Common Name

English

PIPERIDINE, 4-(3-(1H-IMIDAZOL-4-YL)PROPYL)-

Systematic Name

English

4-(3-(1H-IMIDAZOL-5-YL)PROPYL)PIPERIDINE

Systematic Name

English

PIPERIDINE, 4-(3-(1H-IMIDAZOL-5-YL)PROPYL)-

Systematic Name

English

Code System Code Type Description

CAS

768358-61-8

Created by admin on Sat Dec 16 18:11:56 UTC 2023 , Edited by admin on Sat Dec 16 18:11:56 UTC 2023

PRIMARY

EPA CompTox

DTXSID501277310

Created by admin on Sat Dec 16 18:11:56 UTC 2023 , Edited by admin on Sat Dec 16 18:11:56 UTC 2023

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FDA UNII

WR5V5TB2TR

Created by admin on Sat Dec 16 18:11:56 UTC 2023 , Edited by admin on Sat Dec 16 18:11:56 UTC 2023

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WIKIPEDIA

VUF-5681

Created by admin on Sat Dec 16 18:11:56 UTC 2023 , Edited by admin on Sat Dec 16 18:11:56 UTC 2023

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PUBCHEM

10330240

Created by admin on Sat Dec 16 18:11:56 UTC 2023 , Edited by admin on Sat Dec 16 18:11:56 UTC 2023

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Related Record Type Details


					D9SCP0G3HF

HISTAMINE H3 RECEPTOR

TARGET -> INHIBITOR

Comments:

Could have partial agonist activity. 3H-cAMP accumulation

Qualification:

IC50

Amount: