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Details

Stereochemistry UNKNOWN
Molecular Formula C34H38N2O4
Molecular Weight 538.6765
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NAFIVERINE

SMILES

CC(C(=O)OCCN1CCN(CCOC(=O)C(C)C2=CC=CC3=C2C=CC=C3)CC1)C4=CC=CC5=C4C=CC=C5

InChI

InChIKey=ZLFQARCCMWUSQE-UHFFFAOYSA-N
InChI=1S/C34H38N2O4/c1-25(29-15-7-11-27-9-3-5-13-31(27)29)33(37)39-23-21-35-17-19-36(20-18-35)22-24-40-34(38)26(2)30-16-8-12-28-10-4-6-14-32(28)30/h3-16,25-26H,17-24H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C34H38N2O4
Molecular Weight 538.6765
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Nafiverinel, N,N'-di[a-(1-naphthy1)propionyloxy-2-ethyllpiperazine, is a new synthetic antispasmodic, which shows low toxicity and a high myolytic activity on the smooth muscles of the ileum, uterus and coronary vessels.

Approval Year

Sample Use Guides

In Vivo Use Guide
Curator's Comment: rabbit data
300 mg three times every 2 hr
Route of Administration: Intramuscular
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:35:28 GMT 2023
Edited
by admin
on Fri Dec 15 15:35:28 GMT 2023
Record UNII
WLT400RC9Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NAFIVERINE
INN   MI  
INN  
Official Name English
NAFIVERINE [MI]
Common Name English
nafiverine [INN]
Common Name English
DA-914
Code English
1,4-PIPERAZINEDIETHANOL .ALPHA.-METHYL-1-NAPHTHALENEACETATE ESTER
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29698
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
Code System Code Type Description
CAS
5061-22-3
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
SMS_ID
100000084434
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
NCI_THESAURUS
C76461
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
ECHA (EC/EINECS)
225-766-5
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
MERCK INDEX
m361
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY Merck Index
INN
1986
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
FDA UNII
WLT400RC9Q
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
ChEMBL
CHEMBL2107421
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
EVMPD
SUB09123MIG
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID10863486
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
MESH
C002681
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
PUBCHEM
21137
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
DRUG CENTRAL
3790
Created by admin on Fri Dec 15 15:35:28 GMT 2023 , Edited by admin on Fri Dec 15 15:35:28 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY