Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 19:01:33 GMT 2023
by
admin
on
Sat Dec 16 19:01:33 GMT 2023
|
| Protein Type | MONOCLONAL ANTIBODY |
| Protein Sub Type | IGG1 |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
WCK9537JXW
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
12594
Created by
admin on Sat Dec 16 19:01:33 GMT 2023 , Edited by admin on Sat Dec 16 19:01:33 GMT 2023
|
PRIMARY | |||
|
WCK9537JXW
Created by
admin on Sat Dec 16 19:01:33 GMT 2023 , Edited by admin on Sat Dec 16 19:01:33 GMT 2023
|
PRIMARY | |||
|
2756228-84-7
Created by
admin on Sat Dec 16 19:01:33 GMT 2023 , Edited by admin on Sat Dec 16 19:01:33 GMT 2023
|
PRIMARY | |||
|
C199138
Created by
admin on Sat Dec 16 19:01:33 GMT 2023 , Edited by admin on Sat Dec 16 19:01:33 GMT 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_22 | 1_96 |
| 2_22 | 2_96 |
| 2_160 | 2_216 |
| 2_236 | 4_215 |
| 2_277 | 2_337 |
| 1_160 | 1_216 |
| 2_383 | 2_441 |
| 3_23 | 3_88 |
| 3_135 | 3_195 |
| 4_23 | 4_88 |
| 4_135 | 4_195 |
| 1_236 | 3_215 |
| 1_242 | 2_242 |
| 1_245 | 2_245 |
| 1_277 | 1_337 |
| 1_383 | 1_441 |
| Glycosylation Type | MAMMALIAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_313 |
| N | 2_313 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
OR2805 binds to CD163 while also engaging an Fc receptor (FcR) on the same M2 macrophages, resulting in reprogramming of M2 macrophages
and the loss of M2 cell-mediated immune-suppression.
PRECLINICAL
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|
||||
| Molecular Formula | CHEMICAL |
|