Details
Stereochemistry | RACEMIC |
Molecular Formula | C19H20N4O2 |
Molecular Weight | 336.3877 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CCCC(C1)C(=O)N2C3=CC=CC=C3NC(=O)C4=CC=CN=C24
InChI
InChIKey=LPLNSPKKMWHFAU-UHFFFAOYSA-N
InChI=1S/C19H20N4O2/c1-22-11-5-6-13(12-22)19(25)23-16-9-3-2-8-15(16)21-18(24)14-7-4-10-20-17(14)23/h2-4,7-10,13H,5-6,11-12H2,1H3,(H,21,24)
Molecular Formula | C19H20N4O2 |
Molecular Weight | 336.3877 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
Rispenzepine (DF 594) is a muscarinic receptor antagonist. Rispenzepine has high affinity for intestinal muscarinic receptors, with preferential action at M1 and M3 receptor subtypes. This drug shows potent inhibitory effects on intestinal motility. In guinea pigs, rispenzepine significantly increases acetylcholine release in the trachea. A phase II study to test efficacy in asthma patients has been discontinued.
Originator
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:24:34 GMT 2023
by
admin
on
Fri Dec 15 17:24:34 GMT 2023
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Record UNII |
W99LLM73R7
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Record Status |
Validated (UNII)
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Record Version |
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-
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Common Name | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29698
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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Code System | Code | Type | Description | ||
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96449-05-7
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admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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W99LLM73R7
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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CHEMBL2106612
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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SUB10334MIG
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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100000080572
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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129505
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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6521
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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C74175
Created by
admin on Fri Dec 15 17:24:34 GMT 2023 , Edited by admin on Fri Dec 15 17:24:34 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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ENANTIOMER -> RACEMATE | |||
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ENANTIOMER -> RACEMATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |