BELFOSDIL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H50O7P2
Molecular Weight	548.6292
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCOP(=O)(CC(CCOC1=CC=CC=C1)CP(=O)(OCCCC)OCCCC)OCCCC

InChI

InChIKey=QTBMDDQRDDABNC-UHFFFAOYSA-N

InChI=1S/C27H50O7P2/c1-5-9-19-31-35(28,32-20-10-6-2)24-26(18-23-30-27-16-14-13-15-17-27)25-36(29,33-21-11-7-3)34-22-12-8-4/h13-17,26H,5-12,18-25H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C27H50O7P2
Molecular Weight	548.6292
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2550449

Belfosdil (or SR-7037) is an antihypertensive calcium channel blocker.

Approval Year

PubMed

Title	Date	PubMed
A new class of calcium entry blockers defined by 1,3-diphosphonates. Interactions of SR-7037 (belfosdil) with receptors for calcium channel ligands.	1989 Oct 5	2550449
Determination of belfosdil, a new calcium channel blocker, in human plasma by capillary gas chromatography with nitrogen-phosphorus detection.	1990 May 18	2387881
Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix.	2001 May	11334406

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:49:06 GMT 2023` Edited by `admin` on `Fri Dec 15 15:49:06 GMT 2023`
Record UNII	W91CMS1V7Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BELFOSDIL

Official Name

English

belfosdil [INN]

Common Name

English

PHOSPHONIC ACID, (2-(2-PHENOXYETHYL)-1,3-PROPANEDIYL)BIS-, TETRABUTYL ESTER

Common Name

English

TETRABUTYL 2-(2-PHENOXYETHYL)-1,3-PROPYLIDENE DIPHOSPHONATE

Common Name

English

BMY-21891

Code

English

SR-7037

Code

English

BELFOSDIL [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C333