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Details

Stereochemistry ACHIRAL
Molecular Formula CH4N2O
Molecular Weight 61.0479
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of UREA C-13

SMILES

N[13C](N)=O

InChI

InChIKey=XSQUKJJJFZCRTK-OUBTZVSYSA-N
InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)/i1+1

HIDE SMILES / InChI

Molecular Formula CH4N2O
Molecular Weight 61.0479
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. 13C-urea present in drugs which are intended for use in the qualitative detection of 13CO2 in whole blood specimens, collected after the ingestion of 13C-urea. Helicobacter pylori (H. pylori) organisms colonizing the lining of the human stomach, produce urease which converts 13C-urea into 13CO2 and ammonia (NH4+). In the presence of urease associated with gastric H. pylori, 13C-urea is decomposed to 13CO2 and ammonia NH4. The 13CO2 is absorbed in the blood, then exhaled in the breath. This results in an increase in the ratio of 13CO2 to 12CO2 in a TEST breath sample compared to a BASELINE sample.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
BREATHTEK UBT FOR H-PYLORI

Approved Use

The BreathTek UBT Collection Kit is intended for use in the qualitative detection of urease associated with Helicobacter pylori in the human stomach and as an aid in the initial diagnosis and post-treatment monitoring of Helicobacter pylori infection in adult patients.

Launch Date

1996
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:54:37 GMT 2023
Edited
by admin
on Fri Dec 15 15:54:37 GMT 2023
Record UNII
W6KX9E6D8X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
UREA C-13
ORANGE BOOK  
Common Name English
UREA (13C) [JAN]
Common Name English
CARBONE (13) UREA
Common Name English
UREA C-13 [ORANGE BOOK]
Common Name English
UREA 13 C
WHO-DD  
Common Name English
UREA, C-13
Common Name English
13C-UREA
Common Name English
UREA C 13
USP   USP-RS  
Common Name English
CARBON-13 UREA
Common Name English
13-C UREA [EMA EPAR]
Common Name English
IDKIT:HP COMPONENT UREA C-13
Common Name English
Urea 13 C [WHO-DD]
Common Name English
UREA (13C)
JAN  
Common Name English
UREA C 13 [USP IMPURITY]
Common Name English
UREA C 13 [USP MONOGRAPH]
Common Name English
UREA ((SUP 13)C)
Common Name English
13-C-UREA
Common Name English
UREA C 13 [USP-RS]
Common Name English
(13C) UREA
Common Name English
13-C UREA
EMA EPAR  
Common Name English
UREA C-13 COMPONENT OF IDKIT:HP
Common Name English
Classification Tree Code System Code
NDF-RT N0000006999
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
NDF-RT N0000166093
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
NDF-RT N0000166118
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
NDF-RT N0000175886
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
NCI_THESAURUS C1937
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
NDF-RT N0000166118
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
Code System Code Type Description
FDA UNII
W6KX9E6D8X
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
RXCUI
226724
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY RxNorm
ChEMBL
CHEMBL985
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
PUBCHEM
636363
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
DRUG CENTRAL
4323
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
LACTMED
Urea C 13
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
NCI_THESAURUS
C47779
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
CHEBI
32285
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
RS_ITEM_NUM
1706701
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
SMS_ID
100000089540
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
EPA CompTox
DTXSID20973641
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
CAS
58069-82-2
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
DAILYMED
W6KX9E6D8X
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
EVMPD
SUB20015
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
DRUG BANK
DB09510
Created by admin on Fri Dec 15 15:54:38 GMT 2023 , Edited by admin on Fri Dec 15 15:54:38 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY