ACAZICOLCEPT

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:34:50 GMT 2025` Edited by `admin` on `Tue Apr 01 23:34:50 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	W507556HV0
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ACAZICOLCEPT

Official Name

English

ALPN-101

Preferred Name

English

HUMAN INDUCIBLE T-CELL CO-STIMULATOR LIGAND (ICOS LIGAND) N-TERMINAL FRAGMENT (1-122) (VARIANT (N52>H, N57>Y, Q100>R), FUSED VIA PEPTIDYL LINKER 123GGGGSGGGGS132 TO A HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT (133-363) VARIANT (C137>S, L151>A, L152>E, G154>A,

Common Name

English

1-122-INDUCIBLE COSTIMULATORY LIGAND PROTEIN (52-HISTIDINE,57-TYROSINE,100-ARGININE) (HUMAN) FUSION PROTEIN WITH SYNTHETIC PEPTIDE LINKER (GGGGSGGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C REGION VARIANT C-TERMINAL FRAGMENT), DIMER

Common Name

English

ACAZICOLCEPT [USAN]

Common Name

English

acazicolcept [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

712619

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

FDA ORPHAN DRUG

738919

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

Code System Code Type Description

SMS_ID

300000031957

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

PRIMARY

FDA UNII

W507556HV0

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

PRIMARY

USAN

JK-271

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

PRIMARY

CAS

2270247-50-0

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

PRIMARY

NCI_THESAURUS

C179069

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

PRIMARY

INN

11385

Created by admin on Tue Apr 01 23:34:50 GMT 2025 , Edited by admin on Tue Apr 01 23:34:50 GMT 2025

PRIMARY

INN

From	To
1_143	2_143
1_146	2_146
1_19	1_95
2_19	2_95
1_178	1_238
1_284	1_342
2_178	2_238
2_284	2_342

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_84
N	1_119
N	1_214
N	2_84
N	2_119
N	2_214

Related Record Type Details


					W507556HV0

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL