Details
Stereochemistry | ACHIRAL |
Molecular Formula | C13H14N4O2 |
Molecular Weight | 258.2759 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CC2=CC(=CC=C2NC1=O)C3=NNC(=O)CC3
InChI
InChIKey=SUCNEHPNQBBVHQ-UHFFFAOYSA-N
InChI=1S/C13H14N4O2/c1-17-7-9-6-8(2-3-10(9)14-13(17)19)11-4-5-12(18)16-15-11/h2-3,6H,4-5,7H2,1H3,(H,14,19)(H,16,18)
Molecular Formula | C13H14N4O2 |
Molecular Weight | 258.2759 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Prinoxodan (also known as RGW2938) is a benzodiazinone derivative patented by Rorer International (Overseas), Inc as inotropic agents, useful in treating congestive heart failure. Prinoxodan administered intravenously (i.v.) to anesthetized dogs increased contractile force while decreasing arterial pressure and total peripheral resistance (TPR) in a dose-related manner. A single oral dose of Prinoxodan administered to conscious chronically instrumented dogs produced a marked and sustained increase in contractility 15-240 min after treatment.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1706794
Dog 0.3 mg/kg
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:59:01 GMT 2023
by
admin
on
Sat Dec 16 17:59:01 GMT 2023
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Record UNII |
W4VMH2E80M
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C744
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BB-71
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C059401
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SUB10048MIG
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W4VMH2E80M
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DTXSID10149732
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CHEMBL2105205
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5362397
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C74349
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Related Record | Type | Details | ||
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ACTIVE MOIETY |