U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:35:28 GMT 2023
Edited
by admin
on Sat Dec 16 14:35:28 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
VVE4UQ5M6P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Fazpilodemab
INN   USAN  
Official Name English
fazpilodemab [INN]
Common Name English
RO-7040551
Code English
Immunoglobulin G1 [369-serine,371-alanine,410-valine], anti-(human β-Klotho protein) (human monoclonal HKLB4206 γ1-chain), disulfide with monoclonal HKLB4206 κ-chain, (229→225'),(232→228')-bis(disulfide) with immunoglobulin G1 [365-tryptophan] ant
Common Name English
RG-7992
Code English
BFKB-8488A
Code English
BFKB-8488A (BISPECIFIC ANTIBODY DESIGNED TO MIMIC THE METABOLIC HORMONE FGF21).
Common Name English
RG7992
Code English
BFKB8488A
Code English
ANTI-FGFR1/KLB MAB
Common Name English
immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 (fibroblast growth factor receptor 1, FLT2, KAL2)], monoclonal antibody, bispecific; gamma1 heavy chain anti-KLB (1-450) [VH (Homo sapiens IGHV3-66*01 (
Common Name English
FAZPILODEMAB [USAN]
Common Name English
RO7040551
Code English
Code System Code Type Description
NCI_THESAURUS
C188644
Created by admin on Sat Dec 16 14:35:28 GMT 2023 , Edited by admin on Sat Dec 16 14:35:28 GMT 2023
PRIMARY
USAN
KL-213
Created by admin on Sat Dec 16 14:35:28 GMT 2023 , Edited by admin on Sat Dec 16 14:35:28 GMT 2023
PRIMARY
FDA UNII
VVE4UQ5M6P
Created by admin on Sat Dec 16 14:35:28 GMT 2023 , Edited by admin on Sat Dec 16 14:35:28 GMT 2023
PRIMARY
CAS
2517935-02-1
Created by admin on Sat Dec 16 14:35:28 GMT 2023 , Edited by admin on Sat Dec 16 14:35:28 GMT 2023
PRIMARY
INN
12017
Created by admin on Sat Dec 16 14:35:28 GMT 2023 , Edited by admin on Sat Dec 16 14:35:28 GMT 2023
PRIMARY
From To
1_22 1_96
1_143 1_199
1_219 3_214
1_225 2_229
1_228 2_232
1_260 1_320
1_366 1_424
2_22 2_95
2_147 2_203
2_223 4_218
2_264 2_324
2_370 2_428
3_23 3_88
3_134 3_194
4_23 4_92
4_138 4_198
Related Record Type Details
TARGET -> AGONIST
TARGET -> ACTIVATOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL