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Details

Stereochemistry ABSOLUTE
Molecular Formula C60H92N8O11
Molecular Weight 1101.4195
Optical Activity UNSPECIFIED
Defined Stereocenters 11 / 11
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BASIFUNGIN

SMILES

[H][C@@]12CCCN1C(=O)[C@H](CC3=CC=CC=C3)N(C)C(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@]([H])(OC(=O)[C@@H](N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@]([H])(NC2=O)[C@H](C)CC)C(C)(C)O)[C@H](C)CC

InChI

InChIKey=RLMLFADXHJLPSQ-QKCBWMAHSA-N
InChI=1S/C60H92N8O11/c1-17-38(9)46-57(75)65(14)47(36(5)6)52(70)61-42(32-35(3)4)55(73)67(16)50(60(11,12)78)59(77)79-49(39(10)18-2)58(76)66(15)48(37(7)8)53(71)62-43(33-40-26-21-19-22-27-40)54(72)64(13)45(34-41-28-23-20-24-29-41)56(74)68-31-25-30-44(68)51(69)63-46/h19-24,26-29,35-39,42-50,78H,17-18,25,30-34H2,1-16H3,(H,61,70)(H,62,71)(H,63,69)/t38-,39-,42+,43+,44+,45+,46+,47+,48+,49-,50-/m1/s1

HIDE SMILES / InChI

Molecular Formula C60H92N8O11
Molecular Weight 1101.4195
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 11 / 11
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Basifungin, previously known as LY 295337 or aureuobacidin A, is an antifungal agent that inhibits phosphorylceramide synthase. The development of basifungin against mycoses was discontinued.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
VV0USO6I6U
Record Status Validated (UNII)
Record Version