Details
Stereochemistry | ACHIRAL |
Molecular Formula | C12H9NO6 |
Molecular Weight | 263.203 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CON1C=C(C(O)=O)C(=O)C2=C1C=C3OCOC3=C2
InChI
InChIKey=ABQYZRZVRIPTPI-UHFFFAOYSA-N
InChI=1S/C12H9NO6/c1-17-13-4-7(12(15)16)11(14)6-2-9-10(3-8(6)13)19-5-18-9/h2-4H,5H2,1H3,(H,15,16)
Molecular Formula | C12H9NO6 |
Molecular Weight | 263.203 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Miloxacin, an antibacterial agent that was used in veterinary. This drug was also studied for the treatment of acute intestinitis. Experiments in vitro have shown that this compound exhibited significant activities against Escherichia coli, Klebsiella pneumonia, Proteus mirabilis, Proteus vulgaris, and less active against a Pseudomonas aeruginosa infection and inactive at the maximum test doses against a Streptococcus pyogenes infection. Information about the current use of miloxacin is not available.
Approval Year
PubMed
Title | Date | PubMed |
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Studies on quinoline derivatives and related compounds. 5. Synthesis and antimicrobial activity of novel 1-alkoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. | 1977 Jun |
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[Determination of a new antibacterial agent miloxacin by high performance liquid chromatography and ultraviolet spectrophotometry (author's transl)]. | 1979 Jul |
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[Antimicrobial susceptibility patterns of clinical isolates of Pseudomonas cepacia (author's transl)]. | 1979 Oct |
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Determination of miloxacin and metabolites in human serum and urine by high-pressure liquid chromatography. | 1980 Jul |
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[Clinical studies of miloxacin for acute intestinitis (author's transl)]. | 1981 Nov |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7416751
healthy volunteers receiving 500 mg of miloxacin orally after the morning meal.
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:21:38 GMT 2023
by
admin
on
Fri Dec 15 16:21:38 GMT 2023
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Record UNII |
VM4W7043SN
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C258
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SUB08967MIG
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DTXSID70190563
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VM4W7043SN
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37065-29-5
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m7547
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4524
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37614
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C023981
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CHEMBL339309
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100000080635
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C66154
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Related Record | Type | Details | ||
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ACTIVE MOIETY |