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Details

Stereochemistry ACHIRAL
Molecular Formula C15H15Cl2N3O
Molecular Weight 324.205
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Endixaprine

SMILES

OC1CCN(CC1)C2=NN=C(C=C2)C3=CC=C(Cl)C=C3Cl

InChI

InChIKey=COWWILCLLRVLSC-UHFFFAOYSA-N
InChI=1S/C15H15Cl2N3O/c16-10-1-2-12(13(17)9-10)14-3-4-15(19-18-14)20-7-5-11(21)6-8-20/h1-4,9,11,21H,5-8H2

HIDE SMILES / InChI

Molecular Formula C15H15Cl2N3O
Molecular Weight 324.205
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Endixaprine (SR 41378 or 3-(4-hydroxy-1-piperidinyl)-6-(2,4-dichlorophenyl)-pyridazine) is a aminopyridazine derivative. Endixaprine is a nonbenzodiazepine compound with a pharmacological profile similar to barbiturates and benzodiazepines. It possesses anticonflict, anticonvulsant, antianxiety and hypnotic activities in rodents.

CNS Activity

Originator

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
rats: 1.25-20 mg/kg (i.p.); 10-100 mg/kg (p.o.)
Route of Administration: Other
Substance Class Chemical
Record UNII
V8674RM5KM
Record Status Validated (UNII)
Record Version