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Details

Stereochemistry RACEMIC
Molecular Formula C19H18N2O4
Molecular Weight 338.3572
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CIMOXATONE

SMILES

COCC1CN(C(=O)O1)C2=CC=C(OCC3=CC(=CC=C3)C#N)C=C2

InChI

InChIKey=MVVJINIUPYKZHR-UHFFFAOYSA-N
InChI=1S/C19H18N2O4/c1-23-13-18-11-21(19(22)25-18)16-5-7-17(8-6-16)24-12-15-4-2-3-14(9-15)10-20/h2-9,18H,11-13H2,1H3

HIDE SMILES / InChI
Molecular Formula C19H18N2O4
Molecular Weight 338.3572
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Cimoxatone is a fully reversible inhibitor selective for the A form of monoamine oxidase. Oral administration of Cimoxatone increased brain noradrenaline, dopamine, and serotonin and decreased DOPAC , 5-HIAA, and 3-methoxy-4-hydroxyphenylethylene glycol sulfate.

CNS Activity

CNS Active
4,002

Approval Year

Unknown
149,124

PubMed

Patents

US20120142784
1

Sample Use Guides

In Vivo Use Guide
40 mg as a single dose
Route of Administration: Oral
Substance Class Chemical
Record UNII
V6FT1QJ7VL
Record Status Validated (UNII)
Record Version
NIH
NCATS
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