U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Wed Apr 02 19:49:49 GMT 2025
Edited
by admin
on Wed Apr 02 19:49:49 GMT 2025
Protein Type PEPTIDE
Protein Sub Type T-CELL ANTIGEN
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
V62WR73538
Record Status FAILED
Record Version
  • Download
Name Type Language
HUMAN TELOMERASE REVERSE TRANSCRIPTASE PEPTIDE P973
Preferred Name English
Lys-Leu-Phe-Gly-Val-Leu-Arg-Leu-Lys
Systematic Name English
L-Lysyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-leucyl-L-arginyl-L-leucyl-L-lysine
Systematic Name English
L-Lysine, L-lysyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-leucyl-L-arginyl-L-leucyl-
Systematic Name English
hTERT (973-981)
Common Name English
Code System Code Type Description
CAS
255707-29-0
Created by admin on Wed Apr 02 19:49:49 GMT 2025 , Edited by admin on Wed Apr 02 19:49:49 GMT 2025
PRIMARY
FDA UNII
V62WR73538
Created by admin on Wed Apr 02 19:49:49 GMT 2025 , Edited by admin on Wed Apr 02 19:49:49 GMT 2025
PRIMARY
Related Record Type Details
TARGET->VACCINE ANTIGEN
Cancer vaccine regimen combining human telomerase reverse transcriptase (hTERT) peptides with concomitant therapies targeting regulatory T cells (Tregs) and cyclooxygenase-2 (COX2)-mediated immunosuppression.
Related Record Type Details
ACTIVE MOIETY
primary objective was determination of the safety and tolerability of this combination therapy, with anti-cancer activity, immune response and detection of antigen-specific T cells as additional endpoints.
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL