APRONALIDE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C9H16N2O2
Molecular Weight	184.2355
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of APRONALIDE

Structure Search

SMILES

CC(C)C(CC=C)C(=O)NC(N)=O

InChI

InChIKey=KSUUMAWCGDNLFK-UHFFFAOYSA-N

InChI=1S/C9H16N2O2/c1-4-5-7(6(2)3)8(12)11-9(10)13/h4,6-7H,1,5H2,2-3H3,(H3,10,11,12,13)

HIDE SMILES / InChI

Molecular Formula	C9H16N2O2
Molecular Weight	184.2355
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18866296 | https://link.springer.com/article/10.1007/s40278-013-4834-7

Apronalide is an acyclic analog of barbiturates. It was used under tradename "Sedormid" as a sedative an hypnotic agent. In 1934 it was discovered that the drug causes thrombocytopenic purpura. Apronalide is still marketed in Japan, where it is used in combination with caffeine and ibuprofen for the treatment of headache.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:59:00 UTC 2023` Edited by `admin` on `Fri Dec 15 16:59:00 UTC 2023`
Record UNII	V18J24E25E
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

APRONALIDE

Common Name

English

Apronal [WHO-DD]

Common Name

English

N-(AMINOCARBONYL)-2-(1-METHYLETHYL)-4-PENTENAMIDE

Systematic Name

English

(±)-APRONALIDE

Common Name

English

APRONAL

Common Name

English

APRONALIDE, (±)-

Common Name

English

APRONALIDE [MI]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QN05CM12

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

WHO-ATC

N05CM12

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID00862125

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

PRIMARY

DRUG BANK

DB13221

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

PRIMARY

MESH

C005700

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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SMS_ID

100000084902

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

PRIMARY

ECHA (EC/EINECS)

208-443-3

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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FDA UNII

V18J24E25E

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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PUBCHEM

10715

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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EVMPD

SUB21571

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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WIKIPEDIA

APRONAL

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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DRUG CENTRAL

3678

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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MERCK INDEX

m568

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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Merck Index

CAS

528-92-7

Created by admin on Fri Dec 15 16:59:00 UTC 2023 , Edited by admin on Fri Dec 15 16:59:00 UTC 2023

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Related Record Type Details


					V18J24E25E

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