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Details

Stereochemistry RACEMIC
Molecular Formula C9H16N2O2
Molecular Weight 184.2355
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of APRONALIDE

SMILES

CC(C)C(CC=C)C(=O)NC(N)=O

InChI

InChIKey=KSUUMAWCGDNLFK-UHFFFAOYSA-N
InChI=1S/C9H16N2O2/c1-4-5-7(6(2)3)8(12)11-9(10)13/h4,6-7H,1,5H2,2-3H3,(H3,10,11,12,13)

HIDE SMILES / InChI

Molecular Formula C9H16N2O2
Molecular Weight 184.2355
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Apronalide is an acyclic analog of barbiturates. It was used under tradename "Sedormid" as a sedative an hypnotic agent. In 1934 it was discovered that the drug causes thrombocytopenic purpura. Apronalide is still marketed in Japan, where it is used in combination with caffeine and ibuprofen for the treatment of headache.

Approval Year

Substance Class Chemical
Record UNII
V18J24E25E
Record Status Validated (UNII)
Record Version