OXAGRELATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H16N2O4
Molecular Weight	276.2878
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)C1=C(C)C=C2C(CO)=NNC(=O)C2=C1C

InChI

InChIKey=DUQOOLBWGUKRAJ-UHFFFAOYSA-N

InChI=1S/C14H16N2O4/c1-4-20-14(19)11-7(2)5-9-10(6-17)15-16-13(18)12(9)8(11)3/h5,17H,4,6H2,1-3H3,(H,16,18)

HIDE SMILES / InChI

Molecular Formula	C14H16N2O4
Molecular Weight	276.2878
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1554521 | https://www.ncbi.nlm.nih.gov/pubmed/6205194

Oxagrelate (also known as EG626) is an inhibitor of cAMP phosphodiesterase and lead to the platelet aggregation inhibition. Oxagrelate was studied as a smooth muscle relaxant. Information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Inhibition of human and rat platelet aggregation by extracts of Mo-er (Auricularia auricula).	1982 Oct 29	6983740

Substance Class	Chemical Created by `admin` on `Fri Dec 16 16:08:30 UTC 2022` Edited by `admin` on `Fri Dec 16 16:08:30 UTC 2022`
Record UNII	V17MYO89WO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OXAGRELATE

Official Name

English

oxagrelate [INN]

Common Name

English

6-PHTHALAZINECARBOXYLIC ACID, 3,4-DIHYDRO-1-(HYDROXYMETHYL)-5,7-DIMETHYL-4-OXO-, ETHYL ESTER

Common Name

English

SC-32840

Code

English

Ethyl 3,4-dihydro-1-(hydroxymethyl)-5,7-dimethyl-4-oxo-6-phthalazinecarboxylate

Systematic Name

English

NSC-305351

Code

English

OXAGRELATE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C744