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EFLAPEGRASTIM
UT99UG9QJX
US Approved Rx (2022)
First approved in 2022
General
Record Details
Variant Concepts
1
Names
9
Classification
1
Identifiers
11
Subunits
3
Disulfide Links
7
Relationships
1
Active Moiety
1
Modifications
2
Characteristic Attributes
2
EFLAPEGRASTIM
UT99UG9QJX
US Approved Rx (2022)
First approved in 2022
General
Approval Year
2022
324
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
UT99UG9QJX
Record Status
Validated (UNII)
Record Version
17
16
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14
13
12
11
10
9
8
7
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4
3
2
1
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Type
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Type
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Names
9
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Name
Type
Language
Name
Type
Language
eflapegrastim [INN]
Preferred Name
English
EFLAPEGRASTIM
Official Name
English
HM-10460A
Code
English
HNK460
Code
English
HM10460A
Code
English
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2
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Classification
1
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Recombinant Colony Stimulating Factor
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Recombinant Growth Factor
[C530]
Recombinant Hematopoietic Growth Factor
[C2395]
Recombinant Colony Stimulating Factor
[C387]
Recombinant Granulocyte Colony-Stimulating Factor
NCI_THESAURUS
C1287
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Identifiers
11
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Code System
Code
Type
Description
Code System
Code
Type
Description
DRUG BANK
DB15001
PRIMARY
DAILYMED
UT99UG9QJX
PRIMARY
SMS_ID
300000025173
PRIMARY
CAS
1384099-30-2
PRIMARY
USAN
DE-31
PRIMARY
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Subunits
3
Subunit 0
>SUBUNIT_0
Subunit 1
>SUBUNIT_1
Subunit 2
>SUBUNIT_2
Disulfide Links
7
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From
To
From
To
1_3
2_3
1_35
1_95
1_141
1_199
2_35
2_95
2_141
2_199
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
Eflapegrastim-xnst
SUB_CONCEPT->SUBSTANCE
Amount:
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Active Moiety
1
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Related Record
Type
Details
Related Record
Type
Details
UT99UG9QJX
EFLAPEGRASTIM
ACTIVE MOIETY
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Modifications
2
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO ACID SUBSTITUTION
[3_1]
Thr
THREONINE PEG-80 PROLINE
49D6Y89W18
AMINO ACID SUBSTITUTION
[1_1]
Pro
THREONINE PEG-80 PROLINE
49D6Y89W18
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Characteristic Attributes
2
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT
CHEMICAL
72100 Da (average)
Molecular Formula
CHEMICAL
ESTIMATED
C3055H4732N804O923S23
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