Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H26FN3O4 |
| Molecular Weight | 403.4472 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]1(CCN(C1)C2=C(OC)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O)[C@H](C)NC
InChI
InChIKey=SUQUWONDIBHQOZ-NWDGAFQWSA-N
InChI=1S/C21H26FN3O4/c1-11(23-2)12-6-7-24(9-12)18-16(22)8-14-17(20(18)29-3)25(13-4-5-13)10-15(19(14)26)21(27)28/h8,10-13,23H,4-7,9H2,1-3H3,(H,27,28)/t11-,12+/m0/s1
| Molecular Formula | C21H26FN3O4 |
| Molecular Weight | 403.4472 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Premafloxacin is an 8-methoxy fluoroquinolone derivative patented by American pharmaceutical company Warner-Lambert Co. as an antibacterial agent. In preclinical studied. Premafloxacin was equivalent to ciprofloxacin, enrofloxacin, and danofloxacin in activity against the gram-negative bacilli but was much more active than the comparison antimicrobial agents (against the staphylococci, streptococci, and anaerobes. Premafloxacin acts as a topoisomerase IV inhibitor with enhanced activity against Staphylococcus aureus.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:42:41 UTC 2023
by
admin
on
Sat Dec 16 05:42:41 UTC 2023
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| Record UNII |
UOM2HMO524
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
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Code | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C795
Created by
admin on Sat Dec 16 05:42:41 UTC 2023 , Edited by admin on Sat Dec 16 05:42:41 UTC 2023
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| Code System | Code | Type | Description | ||
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100000081427
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C105016
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C66464
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DTXSID70162407
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CHEMBL2105374
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71455
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SUB10025MIG
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143383-65-7
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7333
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GG-29
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UOM2HMO524
Created by
admin on Sat Dec 16 05:42:41 UTC 2023 , Edited by admin on Sat Dec 16 05:42:41 UTC 2023
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PRIMARY |
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