Perzebertinib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H26F2N8O3
Molecular Weight	548.5439
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C2N=CN=C(NC3=CC=C(OC4=CC5=NC=NN5C=N4)C(C)=C3)C2=C1O[C@@H]6CCN(C)CC6(F)F

InChI

InChIKey=PTKRHBXNNDLRPO-OAQYLSRUSA-N

InChI=1S/C27H26F2N8O3/c1-16-10-17(4-6-19(16)39-23-11-22-31-14-34-37(22)15-33-23)35-26-24-18(30-13-32-26)5-7-20(38-3)25(24)40-21-8-9-36(2)12-27(21,28)29/h4-7,10-11,13-15,21H,8-9,12H2,1-3H3,(H,30,32,35)/t21-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C27H26F2N8O3
Molecular Weight	548.5439
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 06:18:00 GMT 2025` Edited by `admin` on `Wed Apr 02 06:18:00 GMT 2025`
Record UNII	UN8TM5120C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

perzebertinib [INN]

Preferred Name

English

Perzebertinib

Official Name

English

5-{[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]oxy}-6-methoxy-N-{3-methyl-4-[([1,2,4]triazolo[1,5-c]pyrimidin-7-yl)oxy]phenyl}quinazolin-4-amine

Systematic Name

English

4-Quinazolinamine, 5-[[(4R)-3,3-difluoro-1-methyl-4-piperidinyl]oxy]-6-methoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)phenyl]-

Systematic Name

English

5-[[(4R)-3,3-Difluoro-1-methyl-4-piperidinyl]oxy]-6-methoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)phenyl]-4-quinazolinamine

Systematic Name

English

Code System Code Type Description

CAS

2414056-31-6

Created by admin on Wed Apr 02 06:18:00 GMT 2025 , Edited by admin on Wed Apr 02 06:18:00 GMT 2025

PRIMARY

PUBCHEM

146448634

Created by admin on Wed Apr 02 06:18:00 GMT 2025 , Edited by admin on Wed Apr 02 06:18:00 GMT 2025

PRIMARY

INN

13444

Created by admin on Wed Apr 02 06:18:00 GMT 2025 , Edited by admin on Wed Apr 02 06:18:00 GMT 2025

PRIMARY

FDA UNII

UN8TM5120C

Created by admin on Wed Apr 02 06:18:00 GMT 2025 , Edited by admin on Wed Apr 02 06:18:00 GMT 2025

PRIMARY

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Amount: