Stereochemistry | ACHIRAL |
Molecular Formula | C30H42N6O5S |
Molecular Weight | 598.757 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN1N=C(C)C2=C1N=CC(C(=O)NCCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)=C2OCCC(C)C
InChI
InChIKey=DIBGLVNSPMMGHO-UHFFFAOYSA-N
InChI=1S/C30H42N6O5S/c1-5-36-28-26(21(4)34-36)27(41-18-16-20(2)3)25(19-32-28)29(37)31-17-15-22-11-13-24(14-12-22)42(39,40)35-30(38)33-23-9-7-6-8-10-23/h11-14,19-20,23H,5-10,15-18H2,1-4H3,(H,31,37)(H2,33,35,38)
Molecular Formula | C30H42N6O5S |
Molecular Weight | 598.757 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Glicaramide is a compound with anti-diabetic (hypoglycemic) activity. It is a second-generation sulfonylurea with a structure similar to glibenclamide, but with 2-methoxy-5-chlorobenzyl replaced by a cyclic acyl group. Peroxisome proliferator-activated receptor gamma (PPARgamma) agonistic activity of glicaramide has been observed as well. Glicaramide has been suggested to have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.