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Details

Stereochemistry ACHIRAL
Molecular Formula C9H5Br2NO
Molecular Weight 302.95
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BROXYQUINOLINE

SMILES

OC1=C(Br)C=C(Br)C2=C1N=CC=C2

InChI

InChIKey=ZDASUJMDVPTNTF-UHFFFAOYSA-N
InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

HIDE SMILES / InChI
Molecular Formula C9H5Br2NO
Molecular Weight 302.95
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Broxyquinoline is an anti-infective agent. It exerts activity against fungi and protozoa. Broxyquinoline (Intestopan) has been used in the treatment of diarrhoeas of different aetiology. Broxyquinoline is able to promote neovascularization.

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
UNIPROT: Q208C2 (Acyl-CoA-binding protein)
2
Inhibitor
8,297
 64.9 µM [IC50]
Trichomonas vaginalis
11
Inhibitor
8,297
Candida albicans
14
Inhibitor
8,297

PubMed

Substance Class Chemical
Record UNII
UK4C618C8T
Record Status Validated (UNII)
Record Version
NIH
NCATS
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