BROXYQUINOLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H5Br2NO
Molecular Weight	302.95
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=C2N=CC=CC2=C(Br)C=C1Br

InChI

InChIKey=ZDASUJMDVPTNTF-UHFFFAOYSA-N

InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

HIDE SMILES / InChI

Molecular Formula	C9H5Br2NO
Molecular Weight	302.95
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.whocc.no/atc_ddd_index/?code=A07AX01&showdescription=yes | https://www.ncbi.nlm.nih.gov/pubmed/4792779 | https://www.ncbi.nlm.nih.gov/pubmed/22167242 | https://www.ncbi.nlm.nih.gov/pubmed/14224900 | https://www.ncbi.nlm.nih.gov/pubmed/14154276 | https://www.ncbi.nlm.nih.gov/pubmed/23207768

Broxyquinoline is an anti-infective agent. It exerts activity against fungi and protozoa. Broxyquinoline (Intestopan) has been used in the treatment of diarrhoeas of different aetiology. Broxyquinoline is able to promote neovascularization.

Approval Year

Targets

Primary Target	Pharmacology	Potency
UNIPROT: Q208C2 (Acyl-CoA-binding protein) 2 Target ID: UNIPROT: Q208C2 (Acyl-CoA-binding protein) Sources: https://www.ncbi.nlm.nih.gov/pubmed/22167242	Inhibitor 8504	64.9 µM [IC50]
Trichomonas vaginalis 11 Target ID: CHEMBL612884 Sources: https://www.ncbi.nlm.nih.gov/pubmed/102108	Inhibitor 8504
Candida albicans 14 Target ID: CHEMBL366 Sources: https://www.ncbi.nlm.nih.gov/pubmed/102108	Inhibitor 8504

PubMed

Title	Date	PubMed
2-[(5,7-Dibromo-quinolin-8-yl)-oxy]-N-(2-meth-oxy-phen-yl)acetamide.	2010-11-24	21589573
Liquid phase microextraction and ultratrace determination of cadmium by modified graphite furnace atomic absorption spectrometry.	2009-06-15	19010596
Solid phase extraction vis-à-vis coprecipitation preconcentration of cadmium and lead from soils onto 5,7-dibromoquinoline-8-ol embedded benzophenone and determination by FAAS.	2006-06-15	18970661
The evaluation of liposome-water partitioning of 8-hydroxyquinolines and their copper complexes.	2006-03-15	16570598
A simple spectrophotometric method for the determination of cadmium in industrial, environmental, biological and soil samples using 5,7-dibromo-8-hydroxyquinoline.	2004-06	15228125
A rapid spectrophotometric method for the determination of molybdenum in industrial, environmental, biological and soil samples using 5,7-dibromo-8-hydroxyquinoline.	2002-04	11999518
A study on the neurotoxicity of broxyquinoline and brobenzoxaldine combination in therapeutic doses.	1986-01	3081428
THE IN VITRO EFFECT OF 8-HYDROXYQUINOLINE DERIVATIVES ON STRAINS OF MYCOBACTERIUM TUBERCULOSIS.	1964-02	14127303

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:29:47 GMT 2025` Edited by `admin` on `Mon Mar 31 18:29:47 GMT 2025`
Record UNII	UK4C618C8T
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

STAROGYN

Preferred Name

English

BROXYQUINOLINE

Official Name

English

BROXYQUINOLINE [MI]

Common Name

English

5,7-DIBROMO-8-QUINOLINOL

Systematic Name

English

NSC-1810

Code

English

Broxyquinoline [WHO-DD]

Common Name

English

DIBROMOXIN

Systematic Name

English

broxyquinoline [INN]

Common Name

English

BROXYQUINOLINE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394