DIATHYMOSULFONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C32H34N4O4S
Molecular Weight	570.702
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C1=C(O)C=C(C)C(=C1)\N=N\C2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)\N=N\C4=CC(C(C)C)=C(O)C=C4C

InChI

InChIKey=KHFUQWURHSKTPO-LBYUQGKWSA-N

InChI=1S/C32H34N4O4S/c1-19(2)27-17-29(21(5)15-31(27)37)35-33-23-7-11-25(12-8-23)41(39,40)26-13-9-24(10-14-26)34-36-30-18-28(20(3)4)32(38)16-22(30)6/h7-20,37-38H,1-6H3/b35-33+,36-34+

HIDE SMILES / InChI

Molecular Formula	C32H34N4O4S
Molecular Weight	570.702
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	2
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5899159 | https://www.ncbi.nlm.nih.gov/pubmed/13402561

Diathymosulfone is an antibacterial agent. It was used as antimycobacterial and leprostatic drug.

Approval Year

PubMed

Title	Date	PubMed
[Sulfone J. 51 in the treatment of leprosy; mode of action].	1955	13299213
[Results of the clinical study of the use of the sulfone J-51 (thymosulfone) in the treatment of pulmonary and osteoarticular tuberculosis].	1955 Dec	13281094
[Treatment of pulmonary tuberculosis with the sulfone J. 51].	1955 Feb	14385278
[Remote results of treatment of leprosy by the sulfone J-51; presentation of patients].	1956 Jul-Aug	13396502
[Trial combined treatment of leprosy by the sulfone J-51 at the Leproserie Saint-Antoine de Harar].	1956 Jul-Aug	13396501
[Thymosulfone in the treatment of leprosy].	1957 Jan	13402561
[Treatment of tuberculosis in the diabetic with sulfone J. 51 (thymosulfone)].	1958 Apr	13555121
[Severe relapse of a lepromatous leper treated for six years by the sulfone J-51].	1959 Aug 29	13809492
[OUR EXPERIENCES WITH DIATHYMOSULFONE + ISONIAZID TREATMENT IN VARIOUS FORMS OF TUBERCULOSIS].	1963 Jun	14070132
[Contributions to the treatment of tuberculosis with combined Timosulfone and INH].	1965	5899159

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:07:08 GMT 2023` Edited by `admin` on `Fri Dec 15 16:07:08 GMT 2023`
Record UNII	UK27RQ38IX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIATHYMOSULFONE

Official Name

English

DI(4-(4-HYDROXY-2-METHYL-5-ISOPROPYLPHENYLAZO)PHENYL)SULFONE

Systematic Name

English

DI(4-(4-HYDROXY-2-METHYL-5-ISOPROPYLPHENYLAZO)PHENYL)SULPHONE

Systematic Name

English

DIATHYMOSULPHONE

Common Name

English

DIATHYMOSULFONE [MI]

Common Name

English

diathymosulfone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C849