ONX-0914

Details

Stereochemistry	ACHIRAL
Molecular Formula	C31H40N4O7
Molecular Weight	580.6719
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)[C@]4(C)CO4)C=C1

InChI

InChIKey=WQAVPPWWLLVGFK-FRDWYVIJSA-N

InChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C31H40N4O7
Molecular Weight	580.6719
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Proteasome subunit beta type-8 3 Target ID: CHEMBL5620 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19525961	Inhibitor 8297		10.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:35:38 GMT 2023` Edited by `admin` on `Sat Dec 16 08:35:38 GMT 2023`
Record UNII	UID7D8IN4Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ONX-0914

Code

English

L-TYROSINAMIDE, N-(2-(4-MORPHOLINYL)ACETYL)-L-ALANYL-O-METHYL-N-((1S)-2-((2R)-2-METHYL-2-OXIRANYL)-2-OXO-1-(PHENYLMETHYL)ETHYL)-

Code

English

ONX0914

Code

English

PR-957

Code

English

Code System Code Type Description

FDA UNII

UID7D8IN4Q