U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 18:24:11 GMT 2023
Edited
by admin
on Sat Dec 16 18:24:11 GMT 2023
Source Materials Class ORGANISM
Source Materials Type VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependoparvovirus
Organism Species adeno associated virus
Infraspecific Type SUBSTRAIN
Infraspecific Name AAV8-hG1.7p.coCNGA3
Part whole
Record UNII
UF5FV8MLZ2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AGURACINGENE CADOPARVOVEC
USAN  
Official Name English
AGURACINGENE CADOPARVOVEC [USAN]
Common Name English
DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS 8 VECTOR AAV-CNGA PROMOTER HG1.7P-REGULATED HUMAN RETINAL CONE CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT .ALPHA.3 CODON-OPTIMIZED GENE CNGA3 PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT FLANKS)
Common Name English
aguracingene cadoparvovec [INN]
Common Name English
AAV-CNGA3
Code English
Code System Code Type Description
FDA UNII
UF5FV8MLZ2
Created by admin on Sat Dec 16 18:24:12 GMT 2023 , Edited by admin on Sat Dec 16 18:24:12 GMT 2023
PRIMARY
CAS
2417550-70-8
Created by admin on Sat Dec 16 18:24:12 GMT 2023 , Edited by admin on Sat Dec 16 18:24:12 GMT 2023
PRIMARY
INN
12077
Created by admin on Sat Dec 16 18:24:12 GMT 2023 , Edited by admin on Sat Dec 16 18:24:12 GMT 2023
PRIMARY
NCI_THESAURUS
C184851
Created by admin on Sat Dec 16 18:24:12 GMT 2023 , Edited by admin on Sat Dec 16 18:24:12 GMT 2023
PRIMARY
USAN
JK-79
Created by admin on Sat Dec 16 18:24:12 GMT 2023 , Edited by admin on Sat Dec 16 18:24:12 GMT 2023
PRIMARY
Related Record Type Details
TARGET->GENE REPLACEMENT
EXPRESSED PROTEIN->VECTOR
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
TRANSGENE UNSPECIFIED SUBSTANCE
9fa977ea
(not in database)