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Details

Stereochemistry RACEMIC
Molecular Formula C14H22N2O2
Molecular Weight 250.3367
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROPETAMIDE

SMILES

CCCNC(=O)C(C)NC1=CC=C(OCC)C=C1

InChI

InChIKey=VVUMWAHNKOLVSN-UHFFFAOYSA-N
InChI=1S/C14H22N2O2/c1-4-10-15-14(17)11(3)16-12-6-8-13(9-7-12)18-5-2/h6-9,11,16H,4-5,10H2,1-3H3,(H,15,17)

HIDE SMILES / InChI

Molecular Formula C14H22N2O2
Molecular Weight 250.3367
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Propetamide (also known as FC 379) is a propionamide derivative patented by All-Union Scientific Research Chemical-Pharmaceutical Institute as an analgesic compound. In mice, Propetamide produced both a depression of spontaneous motility and relaxation of muscular tone. However, Propetamide was less active than meprobamate. Propetamide at 400 mg/kg reduced muscular relaxation in 70% of the animals, while the same effect was obtained in 100% of the animals with meprobamate at 200 mg/kg.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
rat: 300-​400 mg/kg
Route of Administration: Oral
Substance Class Chemical
Record UNII
U9R24EH050
Record Status Validated (UNII)
Record Version