Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H25Cl2N3 |
| Molecular Weight | 414.371 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CCN(CC2=C(C)N(C(=C2)C3=CC=C(Cl)C=C3)C4=CC=C(Cl)C=C4)CC1
InChI
InChIKey=YWZIODCWLMCMMW-UHFFFAOYSA-N
InChI=1S/C23H25Cl2N3/c1-17-19(16-27-13-11-26(2)12-14-27)15-23(18-3-5-20(24)6-4-18)28(17)22-9-7-21(25)8-10-22/h3-10,15H,11-14,16H2,1-2H3
| Molecular Formula | C23H25Cl2N3 |
| Molecular Weight | 414.371 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein. | 2013-02-15 |
|
| Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. | 2013 |
|
| 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. | 2008-06-26 |
|
| New derivatives of BM212: A class of antimycobacterial compounds based on the pyrrole ring as a scaffold. | 2007-01 |
|
| New small-molecule synthetic antimycobacterials. | 2005-06 |
|
| Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class. | 2005-02-15 |
|
| Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212. | 2003-02-20 |
|
| BM 212 and its derivatives as a new class of antimycobacterial active agents. | 2002-11 |
|
| New pyrrole derivatives as antimycobacterial agents analogs of BM212. | 1999-10-18 |
|
| Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. | 1998-11 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:38:30 GMT 2025
by
admin
on
Mon Mar 31 23:38:30 GMT 2025
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| Record UNII |
U9HSU4GZWL
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| Record Status |
Validated (UNII)
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| Record Version |
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456926
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U9HSU4GZWL
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