Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H27N3O4 |
| Molecular Weight | 409.4782 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C(CN2N=C(CCCC3=CC=C(OC(C)(C)C(O)=O)C=C3)NC2=O)C=C1
InChI
InChIKey=PNHFDVSKDSLUFH-UHFFFAOYSA-N
InChI=1S/C23H27N3O4/c1-16-7-9-18(10-8-16)15-26-22(29)24-20(25-26)6-4-5-17-11-13-19(14-12-17)30-23(2,3)21(27)28/h7-14H,4-6,15H2,1-3H3,(H,27,28)(H,24,25,29)
| Molecular Formula | C23H27N3O4 |
| Molecular Weight | 409.4782 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
LY-518674 is a highly potent and selective proliferator-activated receptor (PPAR)-alpha agonist. LY-518674 produced a much greater increase in serum high-density lipoprotein-cholesterol (HDL-c) than the known fibrate drugs. The increase in HDL-c was associated with de novo synthesis of apolipoprotein A-1. It was being developed for the treatment of dyslipidemias with atherogenic potential.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:14:26 GMT 2023
by
admin
on
Fri Dec 15 16:14:26 GMT 2023
|
| Record UNII |
U8I57RC739
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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Code | English |
| Code System | Code | Type | Description | ||
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425671-29-0
Created by
admin on Fri Dec 15 16:14:26 GMT 2023 , Edited by admin on Fri Dec 15 16:14:26 GMT 2023
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CHEMBL424133
Created by
admin on Fri Dec 15 16:14:26 GMT 2023 , Edited by admin on Fri Dec 15 16:14:26 GMT 2023
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135449333
Created by
admin on Fri Dec 15 16:14:26 GMT 2023 , Edited by admin on Fri Dec 15 16:14:26 GMT 2023
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U8I57RC739
Created by
admin on Fri Dec 15 16:14:26 GMT 2023 , Edited by admin on Fri Dec 15 16:14:26 GMT 2023
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DB12988
Created by
admin on Fri Dec 15 16:14:26 GMT 2023 , Edited by admin on Fri Dec 15 16:14:26 GMT 2023
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DTXSID10962564
Created by
admin on Fri Dec 15 16:14:26 GMT 2023 , Edited by admin on Fri Dec 15 16:14:26 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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