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Details

Stereochemistry RACEMIC
Molecular Formula C16H19NO3
Molecular Weight 273.327
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRODOLIC ACID

SMILES

CCCC1(CC(O)=O)OCCC2=C1NC3=C2C=CC=C3

InChI

InChIKey=IZGMROSLQHXRDZ-UHFFFAOYSA-N
InChI=1S/C16H19NO3/c1-2-8-16(10-14(18)19)15-12(7-9-20-16)11-5-3-4-6-13(11)17-15/h3-6,17H,2,7-10H2,1H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula C16H19NO3
Molecular Weight 273.327
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Prodolic acid is an indole derivative patented by American Home Products Corp. as antiinflammatory agent. Prodolic acid acts as non-steroidal anti-inflammatory compound and inhibits bradykinin-induced bronchoconstriction but did not affects histamine-induced bronchoconstriction in the guinea pig. In preclinical studies, Prodolic acid exhibits potent anti-inflammatory activity in adjuvant arthritic rats.

Approval Year

PubMed

PubMed

TitleDatePubMed
Chemistry and antiinflammatory activities of prodolic-acid and related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. 1.
1975 Feb
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:57:37 GMT 2023
Edited
by admin
on Fri Dec 15 18:57:37 GMT 2023
Record UNII
U8EX2DRD73
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PRODOLIC ACID
INN   USAN  
USAN   INN  
Official Name English
1,3,4,9-Tetrahydro-1-propylpyrano[3,4-b]indole-1-acetic acid
Systematic Name English
prodolic acid [INN]
Common Name English
PYRANO(3,4-B)INDOLE-1-ACETIC ACID, 1,3,4,9-TETRAHYDRO-1-PROPYL-
Systematic Name English
AY-23289
Code English
NSC-299133
Code English
AY-23,289
Code English
PRODOLIC ACID [USAN]
Common Name English
Code System Code Type Description
PUBCHEM
37462
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
CAS
36505-82-5
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
EVMPD
SUB10069MIG
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
ChEMBL
CHEMBL1968386
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
MESH
C009795
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
NCI_THESAURUS
C170352
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
CAS
64744-68-9
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
SUPERSEDED
INN
3416
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
SMS_ID
100000081138
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
NSC
299133
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
FDA UNII
U8EX2DRD73
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
EPA CompTox
DTXSID70865820
Created by admin on Fri Dec 15 18:57:37 GMT 2023 , Edited by admin on Fri Dec 15 18:57:37 GMT 2023
PRIMARY
Related Record Type Details
ENANTIOMER -> RACEMATE
ENANTIOMER -> RACEMATE
Related Record Type Details
ACTIVE MOIETY