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Details

Stereochemistry ACHIRAL
Molecular Formula C25H27N2O5S.Na
Molecular Weight 490.547
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EVATANEPAG SODIUM

SMILES

[Na+].CC(C)(C)C1=CC=C(CN(CC2=CC=CC(OCC([O-])=O)=C2)S(=O)(=O)C3=CN=CC=C3)C=C1

InChI

InChIKey=SVNBMCJEDANCKY-UHFFFAOYSA-M
InChI=1S/C25H28N2O5S.Na/c1-25(2,3)21-11-9-19(10-12-21)16-27(33(30,31)23-8-5-13-26-15-23)17-20-6-4-7-22(14-20)32-18-24(28)29;/h4-15H,16-18H2,1-3H3,(H,28,29);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula C25H27N2O5S
Molecular Weight 467.557
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Evatanepag (CP-533,536) is a prostaglandin E2 EP2 receptor agonist. It stimulates new bone formation on trabecular, endocortical, and periosteal surfaces and enhances fracture healing. Evatanepag was under development with Pfizer as a bone formation stimulant for therapeutic use in the healing of fractures.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
5.0 nM [EC50]

PubMed

Substance Class Chemical
Record UNII
U6GMO13KCQ
Record Status Validated (UNII)
Record Version