IDAVERINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H39N3O3
Molecular Weight	417.5848
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CCCC(=O)N1CCC(CC1)C(=O)N(C)C)[C@@H](C)CC2=CC=C(OC)C=C2

InChI

InChIKey=FUWZBLSXACKFQX-IBGZPJMESA-N

InChI=1S/C24H39N3O3/c1-6-26(19(2)18-20-9-11-22(30-5)12-10-20)15-7-8-23(28)27-16-13-21(14-17-27)24(29)25(3)4/h9-12,19,21H,6-8,13-18H2,1-5H3/t19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H39N3O3
Molecular Weight	417.5848
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1820892 | https://www.ncbi.nlm.nih.gov/pubmed/1805238

Idaverine, a muscarinic M2 receptor antagonist, that didn’t prevent motion sickness of cats. Clinical trials for human have shown that the compound was well tolerated.

Approval Year

PubMed

Title	Date	PubMed
Contraction of guinea-pig gallbladder: muscarinic M3 or M4 receptors?	1997-07-30	9298928
Involvement of muscarinic M2 and M3, but not of M1 and M4 receptors in vagally stimulated contractions of rabbit bronchus/trachea.	1994-04	8081071

Patents

Sample Use Guides

In Vivo Use Guide

idaverine was studied in an open, cross-over, partially randomized design after single oral (2 mg) and intravenous (1 and 2 mg doses to 12 healthy male subjects.

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:51:01 GMT 2025` Edited by `admin` on `Mon Mar 31 17:51:01 GMT 2025`
Record UNII	U6212R3SLC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

(+)-1-(4-(ETHYL((S)-P-METHOXY-.ALPHA.-METHYLPHENETHYL)AMINO)BUTYRYL)-N,N-DIMETHYLISONIPECOTAMIDE

Preferred Name

English

IDAVERINE

Official Name

English

idaverine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29698