KETIPRAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H22N2O
Molecular Weight	294.3908
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCCN1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=PXHIRIWYXDUSMR-UHFFFAOYSA-N

InChI=1S/C19H22N2O/c1-20(2)12-7-13-21-17-10-5-3-8-15(17)14-19(22)16-9-4-6-11-18(16)21/h3-6,8-11H,7,12-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H22N2O
Molecular Weight	294.3908
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5459338

KETIPRAMINE, an imipramine derivative, is a tricyclic antidepressant. In clinical trials, it was found to be as effective as imipramine for the depression treatment, with fewer secondary effects.

Approval Year

PubMed

Title	Date	PubMed
Ketipramine in the therapy of depression in outpatients.	1970 Jul-Aug	5459338
Open trial evaluation of keto-imipramine.	1971 Jan	4992567
Ketipramine fumarate as compared to imipramine in depressed outpatients.	1971 May	4998396
Highly efficient and enantioselective cyclization of aromatic imines via directed C-H bond activation.	2004 Jun 16	15186153
A highly enantioselective organocatalytic method for reduction of aromatic N-alkyl ketimines.	2008	18752235

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:51:18 GMT 2023` Edited by `admin` on `Sat Dec 16 16:51:18 GMT 2023`
Record UNII	U5C4H63K5U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

KETIPRAMINE

Common Name

English

5-(3-(DIMETHYLAMINO)PROPYL)-5,11-DIHYDRO-10H-DIBENZ(B,F)AZEPIN-10-ONE

Systematic Name

English

KETIMIPRAMINE

Official Name

English

ketimipramine [INN]

Common Name

English

10H-DIBENZ(B,F)AZEPIN-10-ONE, 5-(3-(DIMETHYLAMINO)PROPYL)-5,11-DIHYDRO-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265