KETIPRAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H22N2O
Molecular Weight	294.3908
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCCN1C2=CC=CC=C2CC(=O)C3=CC=CC=C13

InChI

InChIKey=PXHIRIWYXDUSMR-UHFFFAOYSA-N

InChI=1S/C19H22N2O/c1-20(2)12-7-13-21-17-10-5-3-8-15(17)14-19(22)16-9-4-6-11-18(16)21/h3-6,8-11H,7,12-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H22N2O
Molecular Weight	294.3908
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5459338

KETIPRAMINE, an imipramine derivative, is a tricyclic antidepressant. In clinical trials, it was found to be as effective as imipramine for the depression treatment, with fewer secondary effects.

Approval Year

PubMed

Title	Date	PubMed
A highly enantioselective organocatalytic method for reduction of aromatic N-alkyl ketimines.	2008	18752235
Highly efficient and enantioselective cyclization of aromatic imines via directed C-H bond activation.	2004-06-16	15186153
Ketipramine fumarate as compared to imipramine in depressed outpatients.	1971-05	4998396
Open trial evaluation of keto-imipramine.	1971-01	4992567
Ketipramine in the therapy of depression in outpatients.	1970-07-01	5459338

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:28:18 GMT 2025` Edited by `admin` on `Wed Apr 02 08:28:18 GMT 2025`
Record UNII	U5C4H63K5U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

KETIMIPRAMINE

Preferred Name

English

KETIPRAMINE

Common Name

English

5-(3-(DIMETHYLAMINO)PROPYL)-5,11-DIHYDRO-10H-DIBENZ(B,F)AZEPIN-10-ONE

Systematic Name

English

ketimipramine [INN]

Common Name

English

10H-DIBENZ(B,F)AZEPIN-10-ONE, 5-(3-(DIMETHYLAMINO)PROPYL)-5,11-DIHYDRO-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265