FLUPROQUAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H17FN2O
Molecular Weight	296.3388
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1C(=O)N=C(C2=CC=C(F)C=C2)C3=C1C=C(C)C=C3

InChI

InChIKey=ZWOUXWWGKJBAHQ-UHFFFAOYSA-N

InChI=1S/C18H17FN2O/c1-11(2)21-16-10-12(3)4-9-15(16)17(20-18(21)22)13-5-7-14(19)8-6-13/h4-11H,1-3H3

HIDE SMILES / InChI

Molecular Formula	C18H17FN2O
Molecular Weight	296.3388
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.de/books?id=ka9Earo1mO8C&printsec=frontcover&hl=ru#v=onepage&q&f=false | https://www.ncbi.nlm.nih.gov/pubmed/7043713 | https://www.ncbi.nlm.nih.gov/pubmed/6973990 | https://www.ncbi.nlm.nih.gov/pubmed/6973981

Fluproquazone (RF 46-790 or [4-(p-fluorophenyl-1-isopropyl-7-methyl-2-(1H)quinazolinone]), a quinazoline derivative, is a non-steroidal anti-inflammatory drug. It exerts analgesic and antipyretic properties. It has been withdrawn from the market due to severe hepatotoxicity.

Originator

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:50:39 GMT 2025` Edited by `admin` on `Mon Mar 31 17:50:39 GMT 2025`
Record UNII	U4K85O58HD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUPROQUAZONE

Official Name

English

TORMOSYL

Preferred Name

English

2(1H)-QUINAZOLINONE, 4-(4-FLUOROPHENYL)-7-METHYL-1-(1-METHYLETHYL)-

Systematic Name

English

fluproquazone [INN]

Common Name

English

46-790

Code

English

FLUPROQUAZONE [USAN]

Common Name

English

4-(P-FLUOROPHENYL)-1-ISOPROPYL-7-METHYL-2(1H)-QUINAZOLINONE

Common Name

English

FLUPROQUAZONE [MI]

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2106681