PETRICHLORAL

US Previously Marketed

First approved in 1955

Details

Stereochemistry	MIXED
Molecular Formula	C13H16Cl12O8
Molecular Weight	725.697
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(OCC(COC(O)C(Cl)(Cl)Cl)(COC(O)C(Cl)(Cl)Cl)COC(O)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

InChI

InChIKey=OKACKALPXHBEMA-UHFFFAOYSA-N

InChI=1S/C13H16Cl12O8/c14-10(15,16)5(26)30-1-9(2-31-6(27)11(17,18)19,3-32-7(28)12(20,21)22)4-33-8(29)13(23,24)25/h5-8,26-29H,1-4H2

HIDE SMILES / InChI

Molecular Formula	C13H16Cl12O8
Molecular Weight	725.697
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 955, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Krug, E.E. (1960) Pharmacology in nursing, page 236, retrieved from: https://books.google.ru/books?id=ESttAAAAMAAJ | (1959) Medical Digest, v.5, page 245, retrieved from: https://books.google.ru/books?id=-PYrAQAAMAAJ

Petrichloral is the tetrahemiacetal pentaerythritol derivative of chloral. Animal trials and studies among institutionalized patients offer clinical evidence as to the therapeutic relationship between the drugs. Petrichloral exhibits a hypnotic and sedative action similar to chloral hydrate. It is better tolerated than the later drug.

Approval Year

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L1MPJ
ABI Chem	AC1Q77OY
ChemTik	CTK9A4794
NovoSeek	6519
PubChem	6519	https://pubchem.ncbi.nlm.nih.gov/compound/6519

PubMed

Title	Date	PubMed
Pentaerythritol chloral: a new agent for hypnosis and sedation; preliminary report.	1955 Dec	13268844
Sedative response to pentaerythritol chloral; clinical evaluation of a new chloral derivative in 164 cases.	1958	13592392

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:19:56 UTC 2023` Edited by `admin` on `Fri Dec 15 18:19:56 UTC 2023`
Record UNII	U49LID4UYJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PETRICHLORAL

Official Name

English

petrichloral [INN]

Common Name

English

PENTAERYTHRITOL CHLORAL

Systematic Name

English

PENTAERYTHRITOL CHLORAL [MI]

Common Name

English

Classification Tree Code System Code

DEA NO.

2591